Is Hyperglycemia a Cardiovascular Risk Factor?

Coronary Risk Estimation according to the Framingham-Wilson Score and Impaired Fasting Glucose in Adult Subjects from Maracaibo city, Venezuela

“…Assessment of coronary risk by gender in each glycemic status group revealed that IFG men have a significantly higher risk than their female counterparts, similar to previous results from Modrego et al [47]; however, it should be noted that coronary risk remained similar between genders among diabetics, demonstrating the role of T2DM as a gender-independent cardiovascular risk factor [48]. Although the presence of IFG has been associated with increased cardiovascular risk through its association with comorbities such as dyslipidemia and hypertension [49], several studies have proposed possible mechanisms which chronic IFG may trigger endothelial dysfunction, or at least, play a role in atherogenesis by increasing production of reactive oxygen species [50], advanced glycation endproducts [51], and inducing low-grade inflammation [52]. Likewise, elements such as physical inactivity, lipid-rich and carbohydraterich diets have been linked with prediabetic states [53], yet few studies explore the relationship of these sociodemographic aspects with cardiovascular risk.…”

Atherosclerosis Is Associated with Neutrophil Lymphocyte Ratio As An Inflammatory Marker in Type 2 Diabetes Mellitus Patients with Coronary Artery Disease

“…Our results reinforce the concept that glycemic control plays an important role in the presence of CAD, at least in this group of type 2 DM patients with high cardiovascular risk. 27 Even in non-diabetic individuals HbA1c can be associated with CAD and its severity. 28 In this study, we found a relation of NLR with the presence of coronary artery disease.…”

Occurrence of coronary artery disease in patients with type 2 diabetes mellitus can be predicted by neutrophil lymphocyte ratio

“…Our results reinforce the concept that glycemic control plays an important role in the presence of CAD, at least in this group of type 2 DM patients with high cardiovascular risk. 23 Even in non-diabetic individuals HbA1c can be associated with CAD and its severity. 24 In this study, we found a relationship between NLR and the presence of coronary artery disease.…”