Is Polycystic Ovary Syndrome a Predisposing Factor for Pilonidal Sinus Disease?

Ugurlu, Celil; Yıldırım, Murat; Ozcan, Ozhan; Karayigit, Serkan; Dasiran, Fatih; Okan, İsmail

doi:10.1097/dcr.0000000000002336

Cited by 4 publications

(5 citation statements)

References 32 publications

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“…This article highlights a novel finding of an increased risk of pilonidal sinus (PS) among women with polycystic ovary syndrome (PCOS; 22.5%) compared to the control group (1.7%). 1 This article seems to support the Karydakis theory of pilonidal sinus pathogenesis. However, recently there have been a few articles that challenge this notion.…”

Section: To the Editor—supporting

confidence: 62%

Comment on: Is Polycystic Ovary Syndrome a Predisposing Factor for Pilonidal Sinus Disease?

Raheel

Rhaeel

2022

Diseases of the Colon &Amp; Rectum

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To the Editor-The article "Is Polycystic Ovary Syndrome a Predisposing Factor for Pilonidal Sinus Disease?" by Ugurlu et al piqued our interest. This article highlights a novel finding of an increased risk of pilonidal sinus (PS) among women with polycystic ovary syndrome (PCOS; 22.5%) compared to the control group (1.7%). 1 This article seems to support the Karydakis theory of pilonidal sinus pathogenesis. However, recently there have been a few articles that challenge this notion. According to this theory, soft and macerated hair increases the incidence of PS disease (PSD). As a result, clinicians have started attributing excess sweating and body hygiene as some of the risk factors increasing the incidence of PSD. However, a recent study by Doll et al, in which 100 patients with PS were matched with 100 healthy patients, showed reduced sweating (18.4 ± 1.6 vs 24.2 ± 2.1 µL; p = 0.03). 2 Another study found no correlation between increased fecal and urine contact on the incidence of PS. 3 The article suggests that hirsutism, a clinical manifestation of hyperandrogenism that is common among patients with PCOS, may be linked to PS. However, the Rotterdam consensus used for the diagnosis of PCOS includes anovulatory and polycystic ovaries in the absence of hyperandrogenism as a type of polycystic ovary. 4 This criterion contradicts the authors' line of reasoning. The authors should look into how often and what kind of PS is there in people with different types of PCOS to better understand the risk factors for PS in this group.

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Section: To the Editor—supporting

confidence: 62%

Comment on: Is Polycystic Ovary Syndrome a Predisposing Factor for Pilonidal Sinus Disease?

Raheel

Rhaeel

2022

Diseases of the Colon &Amp; Rectum

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“…Although the patient group had higher mean volume of the left ovaries, but it was at the verge of statistical significance (p=0.057). The difference in ovarian volume between the groups is likely to be explained by the more common presence of PCOS in women with PSD, and the presence of more antral follicles on the right side [ 10 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

“…To the best if our knowledge, there is only one study in the literature that previously reported the relationship between PCOS and PSD. The study by Ugurlu et al [ 10 ] investigated the frequency of PSD in 40 PCOS patients compared to healthy controls, and found a statistically significant increase. On the contrary, our study examined the frequency of PCOS in patients with PSD.…”

Section: Highlight Key Pointsmentioning

confidence: 99%

Analysis of blood parameters and clinical features in women with pilonidal sinus disease: Is there a link between the disease and polycystic ovary syndrome?

Yiğit¹

2023

North Clin Istanbul

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OBJECTIVE Pilonidal sinus disease (PSD) is a common disorder in the sacrococcygeal region and has a lower incidence in female as compared with male patients. The aim of this study is to evaluate clinical, hematological, biochemical, and hormonal parameters in women with PSD, and to determine whether the disease plays a major role in abnormalities of clinical and laboratory findings. This study also brings to the forefront the issue of the association between PSD and polycystic ovary syndrome (PCOS). METHODS The prospective single-center study included women with PSD, and an equal number of healthy women enrolled in the control group (50 women in each arm of the study). Medical history was taken from every patient, and blood tests were performed on all participants. Ultrasound imaging was performed to evaluate the ovaries. RESULTS Both groups were matched for age (p=0.124). The prevalence of obesity and dyslipidemia was significantly higher in women with PSD compared to controls (p=0.046, p=0.008, respectively). The right ovary volume was significantly higher in the study group than the control group (p=0.028). The study group had also significantly higher mean levels of neutrophil, C-peptide, and thyroid stimulating hormone (p=0.047, p=0.031, and p=0.048, respectively). The prevalence of PCOS was higher in patients with PSD, but the difference failed to reach statistical significance (32 vs. 22%, p=0.26). CONCLUSION Based on the findings of our study, some clinical and blood parameters differed significantly between women with and without PSD. Although the present study revealed that the prevalence of PCOS was not significantly different in women with or without PSD, more comprehensive and prospective studies are required.

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“…Although most individuals with PS are diagnosed at the time of acute infection, such as an abscess causing pain and drainage, some have evidence of associated chronic disease when first observed (multiple sinuses or pits) or occult dis-ease‚ as was described in the article by Ugurlu et al 1 The goal of this Turkish study was to evaluate the prevalence of and risk factors for PS in a cohort of women with PCOS compared to those without PCOS. The hospital was in an agricultural region‚ and most of the women worked on farms in addition to doing household activities.…”

mentioning

confidence: 99%

“…T he recent medical literature has highlighted an association between polycystic ovary syndrome (PCOS) and pilonidal disease (PD) in separate studies evaluating postpubertal adolescents and women of child-bearing age, one of which has been featured in this journal. 1,2 PCOS is the most common cause of female infertility and is associated with several other comorbid conditions, including higher risks of dysfunctional uterine bleeding, endometrial carcinoma, obesity, type 2 diabetes, dyslipidemia, hypertension, and possibly cardiovascular disease, all of which can affect both quality of life and, in some cases, longevity. 3,4 The Rotterdam criteria for diagnosis of PCOS are 2 of 3 criteria of hyperandrogenism, ovulatory dysfunction, and polycystic ovaries, plus exclusion of other diagnoses that could result in hyperandrogenism (nonclassical adrenal hyperplasia, the syndromes of severe insulin resistance, androgen-secreting neoplasms, idiopathic hirsutism, and premature adrenarche) or ovulatory dysfunction (hyperprolactinemia and thyroid abnormalities).…”

mentioning

confidence: 99%