Is the Use of Intensity-Modulated Radiotherapy Beneficial for Pancreatic Cancer Patients?

Park, Hee Chul

doi:10.5009/gnl16014

Cited by 2 publications

(2 citation statements)

References 10 publications

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“…2,3 The modulated intensity makes the desirable dose distribution possible, therefore a high radiation dose is delivered to the planning target volume (PTV) while sparing the surrounding critical organs. [4][5][6][7] Inverse treatment planning is one of the peculiar characteristics of IMRT in which no input parameters are determined for the treatment. Instead just the prescription dose of the target and minimum, maximum doses to the organs at risk (OARs) are fed into the treatment planning system (TPS) then the computer will calculate the suitable input beam fluence.…”

Section: Introductionmentioning

confidence: 99%

Quality assurance of intensity modulated radiation therapy treatment planning using head and neck phantom

et al. 2019

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PurposeThe purpose of this study is the verification of intensity modulated radiation therapy (IMRT) head neck treatment planning with one-dimensional and two-dimensional (2D) dosimeters using imaging and radiation oncology core (IROC) Houston head & neck (H&N) phantom.MethodThe image of the H&N phantom was obtained by computed tomography scan which was then transferred to Pinnacle@3 treatment planning system (TPS) for treatment planning. The contouring of the target volumes and critical organ were done manually and dose constraints were set for each organ according to IROC prescription. The plan was optimised by adoptive convolution algorithm to meet the IROC criteria and collapse cone convolution algorithm calculated the delivered doses for treatment. Varian Clinac 2110 was used to deliver the treatment plan to the phantom, the process of irradiation and measurement were repeated three times for reproducibility and reliability. The treatment plan was verified by measuring the doses from thermoluminescent dosimeters (TLDs) and GafChromic external beam therapy 2 films. The agreement between the planned and delivered doses were checked by calculating the percentage dose differences, analysing their isodose line profiles and 2D gamma maps.ResultsThe average percent dose difference of 1·8% was obtained between computed doses by TPS and measured doses from TLDs, however these differences were found to be higher for organ at risk. The film dose profile was well in agreement with the planned dose distribution with distance to agreement of 1·5 mm. The gamma analysis of the computed and recorded doses passed the criteria of 3%/3 mm with passing percentages of >96%, which shows successful authentication of delivered doses for IMRT.ConclusionIMRT pre-treatment validation can be done with IROC anthropomorphic phantoms, which is essential for the delivery of modulated radiotherapies. It was concluded that films and TLDs can be used as quality assurance tools for IMRT.

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Section: Introductionmentioning

confidence: 99%

Quality assurance of intensity modulated radiation therapy treatment planning using head and neck phantom

et al. 2019

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“…154,155 Radiation Therapy is often prescribed in the adjuvant setting following incomplete resection of the tumour or where there are involved margins following surgery although there is little evidence to suggest the use of adjuvant radiation is beneficial in terms of patient survival. [156][157][158] Radiation Therapy also has a recognised role in the treatment of patients with locally advanced disease but who are unsuitable for surgery either as neo-adjuvant treatment with the aim of shrinking the tumour to increase the potential for surgery or as a definitive treatment for patients unsuitable for surgery.…”

Section: Radiation Therapymentioning

confidence: 99%

Patterns of care in patients with pancreatic cancer

Burmeister¹

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Is the Use of Intensity-Modulated Radiotherapy Beneficial for Pancreatic Cancer Patients?

Cited by 2 publications

References 10 publications

Quality assurance of intensity modulated radiation therapy treatment planning using head and neck phantom

Quality assurance of intensity modulated radiation therapy treatment planning using head and neck phantom

Patterns of care in patients with pancreatic cancer

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