Is There a Seasonal Variation in Eosinophilic Esophagitis? - A Single Center Experience

Malhotra, Ashish; Dhadham, Gautamy Chitiki; Galeano, Narmer F.; Akmal, Amer; Baddoura, Walid

doi:10.14309/00000434-201010001-00065

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fourteen studies examined the seasonality of EoE diagnoses; of these, eight noted a seasonal variation in the initial diagnosis of the disease, as reported by the respective authors, with most cases diagnosed in either spring/summer ( n = 7) or summer/fall ( n = 1).…”

Section: Resultsmentioning

confidence: 97%

“…Of the remaining 46 documents retrieved for complete evaluation, 28 were excluded for the following reasons: they lacked data for calculations (20), they contained repeated or duplicated information (6), they were editorials with no original data (1), or they dealt with esophageal eosinophilia but not EoE (1). In the end, 18 studies (comprising 14 full papers and 4 abstracts ) were included in the quantitative summaries of our systematic review (Fig. ).…”

Section: Resultsmentioning

confidence: 99%

“…Some early studies in children and adults had noted an increase in EoE diagnoses during the pollen season, with peaks in spring and summer. This observation supported the hypothesis of a relevant role for aeroallergens in the development and/or recrudescence of EoE in parallel to what happens with other atopic disorders frequently observed in these same patients.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Seasonal distribution of initial diagnosis and clinical recrudescence of eosinophilic esophagitis: a systematic review and meta‐analysis

Lucendo

Arias²,

González³

et al. 2015

Allergy

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Seasonal distribution of initial diagnosis and clinical recrudescence of eosinophilic esophagitis: a systematic review and meta‐analysis

Lucendo

Arias²,

González³

et al. 2015

Allergy

View full text Add to dashboard Cite

show abstract

The Prevalence and Diagnostic Utility of Endoscopic Features of Eosinophilic Esophagitis: A Meta-analysis

Kim¹,

Vance²,

Shaheen³

et al. 2012

Clinical Gastroenterology and Hepatology

298

269

View full text Add to dashboard Cite

Background & Aims Endoscopic findings such as esophageal rings, strictures, narrow-caliber esophagus, linear furrows, white plaques, and pallor or decreased vasculature might indicate the presence of eosinophilic esophagitis (EoE). We aimed to determine the prevalence and diagnostic utility of endoscopic features of EoE. Methods We conducted a systematic review and meta-analysis. PubMed, EMBASE, and GI meeting abstracts were searched to identify studies that included ≥ 10 patients with EoE and reported endoscopic findings. Pooled prevalence, sensitivity, specificity, and predictive values were calculated using random- and mixed-effects models. Results The search yielded 100 articles and abstracts on 4678 patients with EoE and 2742 without (controls). In subjects with EoE, the overall pooled prevalence of esophageal rings was 44%, strictures 21%, narrow-caliber esophagus 9%, linear furrows 48%, white plaques 27%, and pallor/decreased vasculature 41%. Substantial heterogeneity existed among studies. Results from endoscopy examinations were normal in 17% of patients, but this number decreased to 7% when the analysis was limited to prospective studies (P<.05). Overall levels of sensitivity were modest, ranging from 15% to 48%, whereas levels of specificity were greater, ranging from 90% to 95%. Positive predictive values ranged from 51% to 73% and negative predictive values ranged from 74% to 84%. Conclusions There is heterogeneity among studies in the reported prevalence of endoscopic findings in patients with EoE, but in prospective studies, at least 1 abnormality was detected by endoscopy in 93% of patients. The operating characteristics of endoscopic findings alone are inadequate for diagnosis of EoE. Esophageal biopsies should be obtained from all patients with clinical features of EoE, regardless of the endoscopic appearance of the esophagus.

show abstract

Is There a Seasonal Variation in Eosinophilic Esophagitis? - A Single Center Experience

Cited by 2 publications

References 0 publications

Seasonal distribution of initial diagnosis and clinical recrudescence of eosinophilic esophagitis: a systematic review and meta‐analysis

Seasonal distribution of initial diagnosis and clinical recrudescence of eosinophilic esophagitis: a systematic review and meta‐analysis

The Prevalence and Diagnostic Utility of Endoscopic Features of Eosinophilic Esophagitis: A Meta-analysis

Contact Info

Product

Resources

About