Isatin-based three-component synthesis of new spirooxindoles using magnetic nano-sized copper ferrite

Abstract

CuFe2O4 nanoparticles were synthesized and employed as highly efficient catalysts in the three-component synthesis of biologically important spirooxindoles.

Loading of g‐C3N4 on Core‐Shell Magnetic Mesoporous Silica Nanospheres as a Solid Base Catalyst for the Green Synthesis of some Chromene Derivatives under Different Conditions

“…The obtained solid product was filtered and washed with water and ethanol to remove unreacted substrates. The identity of the so‐obtained products was completely confirmed by FTIR, 1 H NMR and 13 C NMR spectra information consistent in comparison with authentic samples [27,48–51] …”

Transition metal-catalyzed synthesis of spirooxindoles

“…An eco-friendly magnetic copper ferrite NPs catalyzed one-pot reaction for the synthesis of spirooxindoles derivative of 63, 64, 164, 165 was reported. 101 The three-component reaction of dicyanomethane 28, Michael-donors and isatin 6 involved 7 mol% of CuFe 2 O 4 NPs as the catalyst and water–ethanol mixture as solvent under reflux temperature ( Scheme 83 ). 80–92% yields were obtained by using 4-hydroxycoumarin 50, 1,3-cyclohexanedione-derivative of 29, barbituric acid-derivative of 30 and thiobarbituric acid-derivative of 30 as Michael-donors.…”

Urea‐Catalysed Access to Novel Spirooxindole Benzopyrans via Domino Multicomponent Cascade: Approach Towards Sustainability

“…), nano‐sized copper ferrite (2016, Khodabakhshi et al . ), 1,4‐Diazabicyclo[2.2.2]octane (DABCO) (2017, Hasaninejad et al . ), and DABCO‐based ionic liquid ([Dabco‐H]Cl) (2018, Xu et al .…”