Iseult/INUMAC 11.7 T Conductor Production Status

Berriaud, Christophe; Bermond, S.; Dechambre, T.; Gheller, Jean-Marc; Juster, F.P.; Nunio, F.; Payn, A.; Schild, T.; Védrine, P.; Gilgrass, G.; Kanithi, H.

doi:10.1109/tasc.2011.2180289

Cited by 8 publications

(2 citation statements)

References 5 publications

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“…Phosphorus is present in tissues especially in the forms of high-energy phosphates (ATP, PCr) on which the brain depends for intracellular signalling pathways, neurotransmission. Hence, 31 P MRS allows for a unique insight into energy metabolism of brain cells. In vivo cerebral 13 C MRS also provides direct non-invasive measurements of 13 C-labeled energy substrates (lactate, glucose, acetate) and neurotransmitters (gamma amino butyric acid (GABA), glutamate) for the study of neurological, neurodegenerative or psychiatric diseases.…”

Section: Beyond Water Mri: Exploring Brain's Chemistry Metabolism And...mentioning

confidence: 99%

Human brain MRI at 500 MHz, scientific perspectives and technological challenges

Bihan¹,

Schild²

2017

Supercond. Sci. Technol.

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The understanding of the human brain is one of the main scientific challenges of the 21st century. In the early 2000s the French Alternative Energies and Atomic Energy Commission launched a program to conceive and build a 'human brain explorer', the first human MRI scanner operating at 11.7 T. This scanner was envisioned to be part of the ambitious French-German project Iseult, bridging together industrial and academic partners to push the limits of molecular neuroimaging, from mouse to man, using ultra-high field MRI. In this article we provide a summary of the main neuroscience and medical targets of the Iseult project, mainly to acquire within timescales compatible with human tolerances images at a scale of 100 μm at which everything remains to discover, and to create new approaches to develop new imaging biomarkers for specific neurological and psychiatric disorders. The system specifications, the technological challenges, in terms of magnet design, winding technology, cryogenics, quench protection, stability control, and the solutions which have been chosen to overcome them and build this outstanding instrument are provided. Lines of the research and development which will be necessary to fully exploit the potential of this and other UHF MRI scanners are also outlined.

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Section: Beyond Water Mri: Exploring Brain's Chemistry Metabolism And...mentioning

confidence: 99%

Human brain MRI at 500 MHz, scientific perspectives and technological challenges

Bihan¹,

Schild²

2017

Supercond. Sci. Technol.

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“…Table I. The SC conductor is a "wire in channel" with a Niobium-Titanium/Copper wire crimped and soldered in the copper stabilizer [4].…”

Section: A Coil Descriptionmentioning

confidence: 99%

Status of the Shielding Coils Fabrication for the Iseult/INUMAC Whole Body 11.75 T MRI Magnet

Quettier

Berriaud

Bourquard

et al. 2015

IEEE Trans. Appl. Supercond.

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A neuroscience research center with very high field MRI equipment has been opened in November 2006 in the Neurospin site at CEA Saclay. One of the imaging systems will require a whole body 11.75-T MRI magnet with a 900 mm warm bore. Operating at a homogeneous field level of 11.75 T, the cryostat has external dimensions of 4.8 m in diameter and 5.0 m in length. With the large aperture and high field strength, this magnet represents a significant challenge when compared to the largest MRI systems built to date. The coil is made of a niobium-titanium conductor cooled by a He II bath at 1.8 K, permanently connected to a cryoplant. The main coil is constructed from a stack of 170 double pancakes and the magnet is actively shielded by two large coils connected in series to fulfil the stray field specifications. The two shielding coils, each of about 4 m in diameter, are presently being manufactured by Alstom STTG Magnets. This paper describes the design of these coils and presents the latest progress of their fabrication. Details are given of the results of the winding and impregnation of the two coils.

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Latest Progress on the Iseult/INUMAC Whole Body 11.7 T MRI Magnet

Védrine

Maksoud

Aubert

et al. 2012

IEEE Trans. Appl. Supercond.

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The Whole Body 11.7 T MRI Magnet is an actively shielded magnet system, with a stored energy of 338 MJ and an inductance of 308 H. Operating at a homogeneous field level of 11.75 T within a 90 cm warm bore, the cryostat has external dimensions of 4.8 m in diameter and 5.0 m in length. It is part of the Iseult/Inumac project, a French-German initiative focused on very-high-magnetic-field molecular imaging to improve sensitivity, spatial, temporal, and spectral resolution for preclinical and/or clinical MR systems. After the qualification of two first unit lengths of 820 m, the NbTi conductor with a current of 1483 A is now being produced at Luvata Waterbury. Winding of the main coil, made of 170 double pancakes, is starting at Alstom Belfort. Several pieces of equipment have already been delivered to the Neurospin site, CEA Saclay,; including the main refrigerator produced by Air Liquide. Several prototypes have been tested and confirmed the soundness of the magnet design. This paper describes the 11.7 T magnet and the latest progress in its design and fabrication.

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Iseult/INUMAC 11.7 T Conductor Production Status

Cited by 8 publications

References 5 publications

Human brain MRI at 500 MHz, scientific perspectives and technological challenges

Human brain MRI at 500 MHz, scientific perspectives and technological challenges

Status of the Shielding Coils Fabrication for the Iseult/INUMAC Whole Body 11.75 T MRI Magnet

Latest Progress on the Iseult/INUMAC Whole Body 11.7 T MRI Magnet

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