Isolated Endocarditis of the Pulmonary Valve Caused by Pasteurella multocida

Graf, Senta; Binder, Thomas; Heger, Maria; Apfalter, Petra; Simon, Nancy; Winkler, Stefan

doi:10.1007/s15010-007-5074-7

Cited by 18 publications

(22 citation statements)

References 19 publications

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“…Leukocyte and neutrophil counts are typically high at the infection site, and inflammation develops very rapidly. In more severe cases, pasteurellosis can rapidly progress to bacteremia (fulminant sepsis) (41, 161,235,241,251,[256][257][258][259][260][261][262][263][264][265][266] and other complications such as osteomyelitis (inflammation of the bone) (155,165,(267)(268)(269), endocarditis (inflammation of the heart) (256,263,(270)(271)(272)(273)(274)(275)(276)(277)(278)(279)(280)(281)(282)(283)(284)(285), and meningitis (inflammation of the meninges) (53, 90, 159, 163, 165, 264, 286-293).…”

Section: Pasteurella and Other Pasteurellaceae Diseases In Humans Pasmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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SUMMARY In a world where most emerging and reemerging infectious diseases are zoonotic in nature and our contacts with both domestic and wild animals abound, there is growing awareness of the potential for human acquisition of animal diseases. Like other Pasteurellaceae , Pasteurella species are highly prevalent among animal populations, where they are often found as part of the normal microbiota of the oral, nasopharyngeal, and upper respiratory tracts. Many Pasteurella species are opportunistic pathogens that can cause endemic disease and are associated increasingly with epizootic outbreaks. Zoonotic transmission to humans usually occurs through animal bites or contact with nasal secretions, with P. multocida being the most prevalent isolate observed in human infections. Here we review recent comparative genomics and molecular pathogenesis studies that have advanced our understanding of the multiple virulence mechanisms employed by Pasteurella species to establish acute and chronic infections. We also summarize efforts being explored to enhance our ability to rapidly and accurately identify and distinguish among clinical isolates and to control pasteurellosis by improved development of new vaccines and treatment regimens.

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Section: Pasteurella and Other Pasteurellaceae Diseases In Humans Pasmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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“…There are several articles reported with P. multocida induced endocarditis involving native heart valves, but all the patients had predisposing medical conditions. 4,5 In our patient, endocarditis affected her native aortic valve. Similar to previously reported cases of native heart valve endocarditis, she was treated with a full course of intravenous antibiotics and a prosthetic valve replacement.…”

Section: Discussionmentioning

confidence: 69%

Pasteurella multocida infective endocarditis in an immunocompetent patient complicated by rhabdomyolysis and permanent hearing loss

Mikaberidz

Taub

2013

Journal of Cardiovascular Disease Research

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Pasteurella multocida is an inhabitant of the oral cavity of a variety of livestock and domestic pet species, especially cats and dogs. The case reported illustrates a 60-year-old, immunocompetent female patient who presented with P. multocida sepsis and aortic valve endocarditis. This required surgical bioprosthetic aortic valve replacement. Investigation also found infection-induced rhabdomyolysis and permanent hearing loss, both previously unassociated with P. multocida infection.

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“…Like other forms of endocarditis, P. multocida IE is also associated with clinical manifestations including arterial emboli (18,22) and mycotic aneurysms (22). The infection appears to show no preference for the valves involved on the left side of the heart, with the aortic and mitral valves being affected nearly equally (13), and with the tricuspid and pulmonic valves having been affected in a patient after a cat bite (23) and in an intravenous drug user (24), respectively.…”

Section: Discussionmentioning

confidence: 96%

“…Such treatment has been successful, and in several cases it has been an imperative intervention for the cure of affected patients (3,19,21,24,31).…”

Section: Discussionmentioning

confidence: 99%

<i>Pasteurella multocida</i> Infective Endocarditis: A Possible Link with Primary Upper Respiratory Tract Infection

et al. 2015

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A 50-year-old Japanese man presented with fever and upper respiratory tract symptoms that required urgent inpatient admission. A physical examination revealed conjunctival hemorrhages and peripheral embolic phenomena. Blood cultures grew Pasteurella multocida, and an echocardiography revealed a mitral valve vegetation suggestive of infective endocarditis (IE), which was confirmed using the Modified Duke Criteria. After several antibiotic regimens proved ineffective, valve replacement was performed, with a good eventual outcome. P. multocida IE is rare and may sometimes have no preceding risk factors. P. multocida infections of the upper respiratory tract are unusual but may be an inciting event for IE. It is essential to check blood cultures and to repeat the performance of physical examinations to appreciate the developing features of IE.

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Isolated Endocarditis of the Pulmonary Valve Caused by Pasteurella multocida

Cited by 18 publications

References 19 publications

Pasteurella multocida: from Zoonosis to Cellular Microbiology

Pasteurella multocida: from Zoonosis to Cellular Microbiology

Pasteurella multocida infective endocarditis in an immunocompetent patient complicated by rhabdomyolysis and permanent hearing loss

<i>Pasteurella multocida</i> Infective Endocarditis: A Possible Link with Primary Upper Respiratory Tract Infection

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