“…Diagnosis is very often a challenge with several reports in the literature of a significantly delayed diagnosis or even an erroneous clinical diagnosis of malignancy (Casolari et al , ; Mathur et al , ; Tiseo et al , ; Pellicioli et al , ; Cocuzza et al , ; Oryan et al , ). Differential diagnosis encompasses other infectious or non‐infectious diseases such as fungal infections (blastomycosis), tertiary syphilis, sarcoidosis, paracoccidioidomycosis, histoplasmosis, tuberculosis, leprosy, lethal midline granuloma, pemphigus vulgaris, pemphigoid, plasmacytic gingivitis, (deficiencies) anemia, leukemia, anti‐neutrophilic cytoplasmic antibody (ANCA)‐associated (Wegener) granulomatosis, and squamous cell carcinoma (Casolari et al , ; Palmeiro et al , ; Pellicioli et al , ).…”