Isolation and characterization of a saponin from Fagonia indica

A New Triterpene Glycoside from Fagonia cretica

“…An aqueous decoction of the aerial parts of the plant is the popular remedy in the indigenous system of medicine for cancer in its early stages and for the treatment of various diseases of digestive and blood vascular system 1-4 . Previously flavonoids and triterpenoidsaponins have been reported from this species [5][6][7] . The ethanopharmacological and chemotaxonomic importance of the genus Fagonia prompted us to investigate the chemical constituents from F. cretica.…”

Triterpenoids and triterpenoid saponins from the aerial parts of Fagonia indica Burm

“…Several triterpenes and saponins have been reported from this genus which include nahagenin, betulic acid (Rahman et al, 1982), hederagenin and ursolic acid (Rahman et al, 1984), 3b, 23-dihydroxy-23,28-di-O-b-D-glucopyranosyl-taraxer-20-en-28-oic acid, 23,28-di-O-3b-O-D-glucopyranosyl-23-hydroxy taraxer-20-en-28 oic acid (Ansari et al, 1987), 21, 22a-epoxy-23-O-b-Dglucopyranosyl-nahagenin (Ansari et al, 1988), 3-sulfate esters of 3b,27-dihydroxyolean-12-en-28-oic acid and 3b-27-dihydroxy-28-carboxy-O-b-D-glucopyranosylolean-12-en (Perrone et al, 2007). In the present article, we report on the isolation and structure elucidation of two new compounds, a triterpenoid glycoside (1), a triterpene (2) and five known compounds (3-7) from the methanol extract of the aerial parts of Fagonia indica Burm.…”

Triterpene saponins from Fagonia scabra Forssk and other Fagonia species

“…A total of forty-nine triterpenoid saponins (1-49) have been identified in the five investigated Fagonia species, F. arabica L. (Miyase et al, 1996a;Shoeb et al, 1994;Perrone et al, 2007), F. cretica L. (Abdel Khalik et al, 2000aBatterjee et al, 2002;Anjum et al, 2014;Saleem et al, 2014), F. glutinosa Delile (Melek et al, 2000), F. indica Burm.f. (Ansari et al, 1987(Ansari et al, , 1988Shaker et al, 1999Shaker et al, , 2000Shaker et al, , 2013Farheen et al, 2015), and F. mollis Delile (Sallam et al, 2014). Their structures are reported in Table 1 and Fig.…”

“…Previous phytochemical studies on Fagonia species demonstrated the presence of flavonoids (Saleh et al, 1990;Al-Wakeel 1992;El-Wakil and Eman, 2007), diterpenoids (Abdel-Kader et al, 1993;Perrone et al 2007;Sallam et al, 2014), sterols glycosides (Shoeb et al 1994), triterpenes (Anjum et al, 2007;Saleem et al, 2014;Farheen et al, 2015) and saponins (Ansari et al, 1988;Miyase et al, 1996a;Melek et al, 2000;Batterjee et al, 2002;Sallam et al, 2014).…”