2018
DOI: 10.1016/j.virusres.2017.11.001
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Isolation and genetic characterization of encephalomyocarditis virus 1 from a deceased captive hamadryas baboon

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Cited by 9 publications
(17 citation statements)
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“…We also performed ML phylogenetic analysis based on nucleotide sequences of P1, P2 and P3 region separately (). Virus names and lineages were annotated to the trees according to the previous study [5]. EMCV-4 was not included in the phylogenetic tree, because only a small part of P1 sequence was available.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…We also performed ML phylogenetic analysis based on nucleotide sequences of P1, P2 and P3 region separately (). Virus names and lineages were annotated to the trees according to the previous study [5]. EMCV-4 was not included in the phylogenetic tree, because only a small part of P1 sequence was available.…”
Section: Resultsmentioning
confidence: 99%
“…Recently, Vyshemirskii et al . have proposed a detailed genetic classification of EMCV based on the nucleotide sequence identity, which contains four members of Cardiovirus A (EMCV-1 to 4) and EMCV-1 is subdivided into seven lineages (A to G) [5].…”
Section: Introductionmentioning
confidence: 99%
“…Reports of pathogenic Mengovirus, EMCV, and FMDV natural isolates carrying short polyC tracts are biased by the methodology used to sequence the tract: Reverse transcriptase and other template-dependent DNA polymerases have difficulty reproducing repetitive sequences with fidelity and inevitably shorten the tract, resulting in cDNA fragments used for sequencing that do not represent faithfully the length of the polyC tract present in the natural isolates. This is reflected by the fact that every time EMCV polyC tract sequencing has been attempted using cDNA intermediates, it resulted in a short polyC tract ranging from 8 to less than 40 nucleotides, while direct assessment of polyC tract length as it appears in the viral RNA through RNase digestion and radiolabeling always results in long tracts ranging from 110 to 160 nucleotides ( Table 1 ) [ 52 56 ]. Consequently, the existence of natural short-tract isolates is questionable, and statements about the effects of polyC tract length on the pathogenicity of these viruses based on sequencing through cDNA intermediates are not reliable.…”
Section: Effects Of Polyc Tract Alterations In Picornavirusesmentioning
confidence: 99%
“…It is necessary to keep in mind that the encephalomyocarditis virus (EMCV) a picornavirus, induces outbreaks of fatal myocarditis in NHP. It was responsible for heart failure, renal failure and cerebral infarction causing the death of bonobos ( Pan paniscus ); gibbons ( Hylobates lar ) (162), Macaca sylvanus (163), and Papio hamadryas (164). EMCV was described as an encephalitis-type illness in humans rarely resulting in severe clinical symptoms (165).…”
Section: Viral Risks For Humans Who Share Ecosystems With Nhpmentioning
confidence: 99%