Isolation and identification of squalene as an antioxidative compound from the fruits of Prunus mume

Abstract

Prunus mume contains an abundance of minerals such as free sugars, sitosterol, calcium, and iron. It is also an alkaline food that has high levels of organic acids, including succinic acid, citric acid, malic acid, and tartaric acid. P. mume has various functionalities as a health food supplement due to its beneficial effects on fatigue, aging, hangovers, and abnormal defecation (Han et al., 2001;Ko et al., 2007;Park et al., 2013). In addition, it contains rutin, lyoniresinol, and mumefural and has bioactive effects such as anti-cancer, anti-diabetes, and anti-hypertensive activities (Hwang, 2008). Therefore, various processed products based on P. mume fruits are being developed. Studies on the physiological activity of P. mume have previously focused on its antioxidant and anti-microbial

Anti-Inflammatory and Antioxidant Properties of Squalene in Copper Sulfate-Induced Inflammation in Zebrafish (Danio rerio)

“…The DPPH radical scavenging assay is widely used to determine the antioxidant activity of natural compounds because of its simplicity, sensitivity, comparable nature, and reproducibility [33][34][35]. The extract of Prunus mume (squalene-rich) had a good DPPH free radical scavenging ability, and its ethanol extract had the highest antioxidant activity (96.08-97.71%), whereas its water extract had the lowest antioxidant activity (76.09%) [36]. In our study, the free radical scavenging rate of the 1% squalene treatment group was 32% (Figure 2).…”