Isolation, characterization and investigation of Plantago ovata husk polysaccharide as superdisintegrant

Pawar, Harshal Ashok; Varkhade, Chhaya

doi:10.1016/j.ijbiomac.2014.05.019

Cited by 34 publications

(21 citation statements)

References 7 publications

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“…According to Pawar and Varkhade (), the seeds of PO consist in 35% of soluble and 65% insoluble polysaccharides (cellulose, hemicellulose, and lignin). The seeds contain arabinose, xylose, galactose, and rhamnose.…”

Section: Introductionmentioning

confidence: 99%

“…It was demonstrated (Sukhija, Singh, & Riar, ) that the psyllium hydrocolloid has a large potential to be used in the production of edible films with interesting properties, that is, high elasticity and low water vapor permeability, elongation and solubility in water, and a hydrophobic surface. Pawar and Varkhade () proved that the polysaccharide of P. ovata husks can be used as a disintegrating agent in the development of fast‐dissolving tablets.…”

Section: Introductionmentioning

confidence: 99%

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Seeds of Plantago psyllium and Plantago ovata: Mineral composition, grinding, and use for gluten‐free bread as substitutes for hydrocolloids

Ziemichód

Wójcik

Różyło

2018

J Food Process Engineering

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The aim of the study was to evaluate the physicochemical characteristics, grinding, and possibility of whole seeds of Plantago psyllium (PP) and Plantago ovata (PO) application as an alternative to hydrocolloid for gluten‐free bread baking. The procedure of seeds swelling was proposed, trace elements and physical properties of seeds were determined. The grinding energy of seeds and the baking of gluten‐free bread with the addition of whole and grinded form of seeds was made. The seeds of PP and PO are a rich source of trace elements, such as zinc, manganese copper, potassium, magnesium, and calcium. These seeds swell very quickly. PO swells faster at lower temperatures than PP. Grinded seeds of two types of studied Plantago can be used as substitutes for hydrocolloids, they caused a considerable increase in the gluten‐free dough yield (from 200 to 240%) and beneficially affected the texture of the crumb. Practical applications Similarly to fiber the seeds of PP or PO can also be used as replacements for hydrocolloids in the production of gluten‐free bread. The use of whole seeds does not require complicated procedures of fiber extraction, it also has much higher efficiency. Our research allowed to identify a hummer mill on which satisfactory results of Plantago seeds were obtained. PO compared to PP has the seeds that are more susceptible to grinding, their grinding energy is much lower. Characterization of the physical properties of seeds will allow adaptation of processing in the future. Plantago seeds swell intensely in water at different rates depending on the temperature. As a source of trace elements such as zinc, manganese copper, potassium, magnesium, and calcium, whole seeds of Plantago can be a valuable functional food additive.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Seeds of Plantago psyllium and Plantago ovata: Mineral composition, grinding, and use for gluten‐free bread as substitutes for hydrocolloids

Ziemichód

Wójcik

Różyło

2018

J Food Process Engineering

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“…Since natural disintegrants are preferred due to their non-toxicity [16] and they generally reduce in vitro dissolution time and increase the water absorption ratio [25], in this study we investigated the application of the natural disintegrant psyllium ( Plantago ovata Forsk) husk powder for the manufacture of orodispersible meloxicam tablets. Psyllium husk polysaccharide isolated by the solvent precipitation method was successfully used as superdisintegrant for valsartan orodispersible formulation [26], demonstrating an in vitro disintegration time of 20.34 s, a wetting time of 12.60 s, a water absorption ratio of 143.37, and a cumulative drug release of ~75% after 2 min. A cumulative drug release of nearly 100% after 8 min was reported for a 7.5% psyllium husk polysaccharide formulation [26].…”

Section: Introductionmentioning

confidence: 99%

“…Psyllium husk polysaccharide isolated by the solvent precipitation method was successfully used as superdisintegrant for valsartan orodispersible formulation [26], demonstrating an in vitro disintegration time of 20.34 s, a wetting time of 12.60 s, a water absorption ratio of 143.37, and a cumulative drug release of ~75% after 2 min. A cumulative drug release of nearly 100% after 8 min was reported for a 7.5% psyllium husk polysaccharide formulation [26]. Psyllium husk mucilage was used for prochlorperazine maleate fast disintegration tablets, demonstrating an in vitro dispersion time of 8 s, a wetting time of 11 s, and a water absorption ratio of 86%; a faster drug release (t 50% 3.3 min) was reported for the 8% psyllium husk mucilage formulation [6].…”

Section: Introductionmentioning

confidence: 99%

Psyllium (Plantago Ovata Forsk) Husk Powder as a Natural Superdisintegrant for Orodispersible Formulations: A Study on Meloxicam Tablets

et al. 2019

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(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2) Methods: The tablets were prepared using different concentrations of psyllium husk by direct compression. Bulk density, tapped density, hardness, friability, in vitro disintegration, and dissolution time tests were used to assess the quality of the formulations. (3) Results: Psyllium husk powder significantly increased the dissolution rate of meloxicam. The formulation containing 16 mg of psyllium husk powder showed the lowest wetting time, the highest water absorption ratio, and the lowest disintegration time compared to the control and to the other formulations. These effects may be attributed to the rapid uptake of water due to the vigorous swelling ability of psyllium husk powder. (4) Conclusions: The powder could be recommended as an effective natural superdisintegrant for orodispersible formulations.

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“…Arabinoxylan is usually considered to play in beneficial roles in stimulating prebiotic growth [1,2], reducing cardiovascular risk [3], and exhibiting immunoregulation [4] and anti-tumor [5] activities. Psyllium, a mucilaginous polysaccharide material from seed husks, is also an excellent source of arabinoxylan [6,7,8,9,10].…”

Section: Introductionmentioning

confidence: 99%

Structural Features of Alkaline Extracted Polysaccharide from the Seeds of Plantago asiatica L. and Its Rheological Properties

et al. 2016

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Abstract:Polysaccharide from the seeds of Plantago asiatica L. has many bioactivities, but few papers report on the structural and rheological characteristics of the alkaline extract. The alkaline extracted polysaccharide was prepared from seeds of P. asiatica L. and named herein as alkaline extracted polysaccharide from seeds of P. asiatica L. (PLAP). Its structural and rheological properties were characterized by monosaccharide composition, methylation, GC-MS and rheometry. PLAP, as an acidic arabinoxylan, was mainly composed of 1,2,4-linked Xylp and 1,3,4-linked Xylp residues. PLAP solution showed pseudoplastic behavior, and weak gelling properties at high concentration. Sodium and especially calcium ions played a significant role in increasing the apparent viscosity and gel strength.

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Isolation, characterization and investigation of Plantago ovata husk polysaccharide as superdisintegrant

Cited by 34 publications

References 7 publications

Seeds of Plantago psyllium and Plantago ovata: Mineral composition, grinding, and use for gluten‐free bread as substitutes for hydrocolloids

Seeds of Plantago psyllium and Plantago ovata: Mineral composition, grinding, and use for gluten‐free bread as substitutes for hydrocolloids

Psyllium (Plantago Ovata Forsk) Husk Powder as a Natural Superdisintegrant for Orodispersible Formulations: A Study on Meloxicam Tablets

Structural Features of Alkaline Extracted Polysaccharide from the Seeds of Plantago asiatica L. and Its Rheological Properties

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