Isolation of a novel leguminous lysozyme and study on the antifungal activity

Wang, Shaoyun; Ye, Xiuyun; Rao, Pingfan

doi:10.1016/j.foodres.2011.07.039

Cited by 8 publications

(2 citation statements)

References 27 publications

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“…A novel plant lysozyme was isolated in 2005 [ 67 ] from the mung bean ( Phaseolus mungo ), with a molecular weight of 14.4 kDa, and exhibited antifungal activity toward Fusarium solani , Pythium aphanidermatum , Sclerotium rolfsii , and Botrytis cinerea , and antibacterial action against Staphylococcus aureus . A similar antifungal and antibacterial activity was found in the case of lysozyme isolated from Canadian cranberry beans ( Phaseolus vulgaris ) [ 68 ].…”

Section: Sourcessupporting

confidence: 62%

Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic

Ferraboschi

Ciceri

Grisenti³

2021

Antibiotics

209

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Lysozyme is a ~14 kDa protein present in many mucosal secretions (tears, saliva, and mucus) and tissues of animals and plants, and plays an important role in the innate immunity, providing protection against bacteria, viruses, and fungi. Three main different types of lysozymes are known: the c-type (chicken or conventional type), the g-type (goose type), and the i-type (invertebrate type). It has long been the subject of several applications due to its antimicrobial properties. The problem of antibiotic resistance has stimulated the search for new molecules or new applications of known compounds. The use of lysozyme as an alternative antibiotic is the subject of this review, which covers the results published over the past two decades. This review is focused on the applications of lysozyme in medicine, (the treatment of infectious diseases, wound healing, and anti-biofilm), veterinary, feed, food preservation, and crop protection. It is available from a wide range of sources, in addition to the well-known chicken egg white, and its synergism with other compounds, endowed with antimicrobial activity, are also summarized. An overview of the modified lysozyme applications is provided in the form of tables.

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Section: Sourcessupporting

confidence: 62%

Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic

Ferraboschi

Ciceri

Grisenti³

2021

Antibiotics

209

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“…From this perspective, legumes have been extensively studied phytochemically finding out several types of compounds such as alkaloids, non-protein amino acids, amines, flavonoids, isoflavonoids, coumarins, phenylpropanoids, anthraquinones, terpenes, cyanogenic glycolsides, protease inhibitors, chitinases and lectins (Carlini and Grossi-de-Sa', 2002;Wink and Mohamed, 2003). Other researchers have detected proteins that protect legumes from pathogens and predators, such as arcelin, α-amylase inhibitor, vicilins, trypsin inhibitor, canatoxin, soybean cystatins, chymotrypsin inhibitors, lysozymes, ribosome inactivating proteins, antifungal proteins, and small cysteine-rich proteins, including plant defensins (Chen et al, 2002;Ye and Ng, 2003;Wang et al, 2005Wang et al, , 2007Wang et al, , 2012Wong et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Assessment of Phaseolus vulgaris L and Vigna unguiculata (L.) Walp leaves for antifungal metabolites against two bean fungal pathogens Colletotricum lindemuthianum and Phaeoisariopsis griseola

Norena-Ramirez¹,

Velasguez-Ballesteros²,

Murillo-Perea³

et al. 2014

Afr. J. Biotechnol.

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The antifungal potential of hydro-ethanolic leaf extracts of bean varieties was analyzed by bioautography, assessing the contribution of defense molecules of proteic nature against two bean fungal pathogens Colletotricum lindemuthianum and Phaeoisariopsis griseola, also, the Rf values and relative activities of separated compounds were determined; these compounds were in a range of medium polarity to high polarity. The bioactivity expressed by the studied bean varieties could be correlated with the presence of proteic nature compounds, in joint action with secondary plant metabolites. There was some similarity in the chemical composition of the components of the extracts. The varieties G18350, G14241, G1320 CIAT and Vigna ungiculata were the most promising for isolating antifungal compounds. The results demonstrate the value of bioautography as a simple and cheap method to examine plant extracts with antifungal activity.

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Purification and characterization of lysozyme from filipino venus, Ruditapes philippinarum

Kim

Park

Jeong

2012

Food Sci Biotechnol

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Isolation of a novel leguminous lysozyme and study on the antifungal activity

Cited by 8 publications

References 27 publications

Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic

Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic

Assessment of Phaseolus vulgaris L and Vigna unguiculata (L.) Walp leaves for antifungal metabolites against two bean fungal pathogens Colletotricum lindemuthianum and Phaeoisariopsis griseola

Purification and characterization of lysozyme from filipino venus, Ruditapes philippinarum

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