Isolation of an antibacterial sesquiterpenoid from Warburgia salutaris

Rabe, T.; Staden, J. Van

doi:10.1016/s0378-8741(00)00293-2

Cited by 101 publications

(69 citation statements)

References 15 publications

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“…It is known that some plants are rich in secondary metabolites such as tannins, alkaloids, flavonoids, phenols, steroids, and volatile oils which are responsible for therapeutic activities (Cowan, 1999;Rabe & Vanstoden, 2000). Also the use of different plant parts, mostly their decoctions, infusions, oral administration and others have been used as popular medicine for various diseases.…”

mentioning

confidence: 99%

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of Boerhavia diffusa L.

Akinnibosun¹,

Akinnibosun²,

Ogedegbe³

2010

Science World Journal

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confidence: 99%

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of Boerhavia diffusa L.

Akinnibosun¹,

Akinnibosun²,

Ogedegbe³

2010

Science World Journal

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“…In general secondary metabolites present in plants have been reported by Rabe (2000) to be responsible for therapeutic activity. Singh & Bhat (2003) reported that flavonoids are responsible for the antimicrobial activity associated with some ethnomedicinal plants.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical screening and susceptibility of bacteria pathogens to extracts of Evolvulus alsinoides

Omogbai¹,

Eze²

2011

Science World Journal

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The in vitro antibacterial activity of ethanolic and aqueous extract of the whole plant (leaves and twigs) of Evolvulus alsinoides was investigated on gram-positive and gram-negative bacteria by agar well diffusion technique. The results indicate that glycosides, alkaloids, saponins, tannins, flavonoids and volatile oil were better extracted in ethanol than water. The ethanolic extract of the plant had MIC values ranging from 16mg/ml to 512.5mg/ml. The least MIC was 16mg/ml against Salmonella typhi while Bacillus cereus and Staphylococcus aureus showed the highest MIC of 512.5 mg/ml. In the aqueous extract the MIC ranged between 512.5mg/ml to >1025mg/ml. Salmonella typhi, Micrococcus luteus and Staphylococcus aureus were not inhibited by the water extract.

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“…1,2 As pre the World Health Organization reports majority of the world populations still depends on traditional medicines for their psychological and physical health requirements, 3 mainly because of the two reasons first they cannot afford the products of Western pharmaceutical industries, 4 second with their side effects and lack of healthcare facilities. 5 Secondary metabolites are derived from plant source and constitute an important source of microbicides, pesticides and many pharmaceutical drugs from a long period of time medicinal plants or their secondary metabolites have been directly or indirectly playing an important role in the human society to combat diseases.…”

Section: Introductionmentioning

confidence: 99%

Biological activity and phytochemical screening of different extracts of Sida cordata (Burm.F.) borssum root

2020

IJCAAP

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In the present study was designed to evaluate antimicrobial, anthelminthic activity and phytochemical analysis of different extracts of Sida cordata (Burm. f.) borssum root rxtract was prepared using different solvents like chloroform, petroleum ether, ethylacetate, ethanol, and water (aqueous extract). By using agar well diffusion method, the antibiotic activity of different extract was evaluated and minimum inhibitory concentration (MIC) by 96 well resazurin based microtiter dilution the test organisms were Escherichia coli, Staphylococcus aureus, Lacto bacillus Pseudomonas aeroginosa, Candida albicans, Aspergillus niger. Among the different the extracts (ethanolic and aqueous) showed significant antimicrobial activity against Staphylococcus aureus, Escherichia coli, Lacto bacillus, Pseudomonas aeroginosa, Candida albicans and Aspergillus niger. Against S.aureus, aqueous extract showed better activity (20mm, MIC 0.187 mg/ml) followed by Ethanol extract (15mm with MIC 0.390 mg/ml), further the aqueous extract showed activity against Pseudomonas aeruginosa, (15mm, MIC 1.5 mg/ml) followed by Ethanol extract (12mm with MIC 0.375 mg/ml) and same was observed for Lactobacillus (19mm). In terms of anthelmintic activity against Pheretima posthuma (Indian earthworm) aqueous extract of the root exhibited significant activity in the concentration of 100mg/ml with 22.0 and 39 minutes for paralysis and death, respectively and that of standard drug Albendazole was 20 and 38.00 minutes. The aqueous extract showed significantly better effect comparable to standard and hence higher anthelmintic activity.

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Isolation of an antibacterial sesquiterpenoid from Warburgia salutaris

Cited by 101 publications

References 15 publications

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of <i>Boerhavia diffusa</i> L.

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of <i>Boerhavia diffusa</i> L.

Phytochemical screening and susceptibility of bacteria pathogens to extracts of <i>Evolvulus alsinoides</i>

Biological activity and phytochemical screening of different extracts of Sida cordata (Burm.F.) borssum root

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