Isolation of Fungi by Standard Laboratory Methods in Patients With Chronic Rhinosinusitis

Lebowitz, Richard A.; Waltzman, Michael N.; Jacobs, Joseph B.; Pearlman, Amy; Tierno, Philip M.

doi:10.1097/00005537-200212000-00012

Cited by 31 publications

(27 citation statements)

References 8 publications

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“…The literature is quite controversial about the real role of fungi in CRS and we agree with most authors 4,7,9,11,17 that consider that the simple identification of the fungus is not enough for diagnosis, which should be performed together with surgical and clinical pathological findings.…”

Section: Discussionsupporting

confidence: 72%

Rinossinusite fúngica em pacientes com infecção nasossinusal crônica

Dall’Igna

Palombini

Anselmi³

et al. 2005

Rev. Bras. Otorrinolaringol.

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Aim:Fungal rhinosinusitis in patients with chronic sinusal disease study. In the past decades, there has been an increase in fungal infections, and fungal rhinosinusitis (FRS) has been diagnosed more frequently. Knowing the fungal flora, its prevalence and symptomatic presentation in patients with chronic rhinosinusitis (CRS) will allow a better understanding of this disease, permitting a correct diagnosis, and treatment and formulating its prognosis. Study design: clinical retrospective with transversal cohort. Material and Method: 62 patients diagnosed with FRS were selected among 890 cases of CRS undergoing endoscopic surgery. We assessed clinical history otolaryngologic examination with nasal videoendoscopy, CT scan, microbiologic and histopatologic tests. Results: The prevalence of FRS was 6.7% and the fungal type most frequently found was the gender Aspergillus. Fungal ball was found in more than half the cases, and allergic fungal rhinosinusitis (AFRS) in more than one third of the patients. Evolution after endoscopic sinus surgery was more favorable in patients with fungus ball, with a minor number of recurrences. Conclusions: The symptomatic evolution following endoscopic surgery was more favorable in patients with fungal ball, who require a lower number of re-interventions.

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Section: Discussionsupporting

confidence: 72%

Rinossinusite fúngica em pacientes com infecção nasossinusal crônica

Dall’Igna

Palombini

Anselmi³

et al. 2005

Rev. Bras. Otorrinolaringol.

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“…Therefore, fungal sensitization was an important factor to include in an animal model of fungal sinusitis. A. fumigatus and A. alternata were chosen for this study as they are 2 of the most commonly identified species from the sinuses of CRS patients, 12 and antigenic solutions of these species are commercially available for sensitization and skin-prick testing. We successfully induced type I hypersensitivity 3 to A. alternata and A. fumigatus antigens according to skin-prick test results in 10 in 22 (45%) inoculated animals.…”

Section: Discussionmentioning

confidence: 99%

A sheep model to investigate the role of fungal biofilms in sinusitis: fungal and bacterial synergy

Boase

Valentine

Singhal

et al. 2011

Int Forum Allergy Rhinol

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“…The fungal detection rates were higher than those reported in other studies in immunocompetent patients with CRS lacking typical clinical signs of fungal disease. 25,26 The higher detection rate may be explained by an additive effect of the various sensitive methods used. In contrast, cultural detection of fungi in approximately 90% of patients with CRS has been reported recently.…”

Section: Discussionmentioning

confidence: 99%