Isolation of infectious bovine rhinotracheitis virus from Mustelidae

Porter, Davidd .; Larsen, Austin E.; Cox, Nancy A.

doi:10.1128/jcm.1.1.112-113.1975

Cited by 23 publications

(8 citation statements)

References 1 publication

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“…The infectious bovine rhinotracheitis virus (IBR) belongs to the family Herpesviridae. There is only one published case report of spontaneous IBR infection in a ferret [100]. The virus was isolated from the liver, the spleen, and the lungs of a clinically normal ferret.…”

Section: Infectious Bovine Rhinotracheitis Virusmentioning

confidence: 99%

Viral diseases of ferrets

Langlois

2005

Veterinary Clinics of North America: Exotic Animal Practice

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Distemper and rabies vaccination are highly recommended because of the almost invariable fatal outcome of these conditions. Vaccination should constitute an important part of a ferret's preventative medicine program. With the current and anticipated development and licensing of new vaccines, practitioners are invited to gain awareness of the latest vaccine information. Establishment of a practice vaccination protocol with regards to the site of administration of rabies and distemper vaccines is paramount to document any future abnormal tissue reactions. Influenza is the most common zoonotic disease that is seen in ferrets. Although it generally is benign in most ferrets, veterinarians must take this condition seriously. The characteristic continuous antigenic variation of this virus may lead to more virulent strains; the recent emergence of avian influenza virus outbreaks; and the increased susceptibility of elderly, young, and immunosuppressed individuals.

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Section: Infectious Bovine Rhinotracheitis Virusmentioning

confidence: 99%

Viral diseases of ferrets

Langlois

2005

Veterinary Clinics of North America: Exotic Animal Practice

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“…In addition, ferrets have been experimentally infected with pseudorabies (1 8) and infectious bovine rhinotracheitis (IBR) viruses (23). Additionally, IBR virus has been isolated from a clinically normal ferret (19).…”

Section: Introductionmentioning

confidence: 99%

Intranasal Infection of Ferrets (Mustela putorius furo) with Canine Parainfluenza Virus

Durchfeld

Baumgärtner

Krakowka

1991

Journal of Veterinary Medicine, Series B

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Immunocompetent and cyclophosphamide-immunosuppressed ferrets were intranasally infected with canine parainfluenza virus (CPIV) and observed for clinical signs, histolopathologic lesions, the immunocytochemical demonstration of CPIV antigen in the respiratory tract and scanning electron microscopic alterations of the tracheal epithelium until 36 days post infection (p. i.). In both groups, clinical signs were minimal, restricted to the upper respiratory tract and consisted of cough elicited by tracheal compression between 3 and 7 days p. i. Microscopically, inflammatory and degenerative lesions were observed in the trachea and less frequently in the nasal cavity; bronchiolitis or interstitial pneumonia was not demonstrated. By immunocytochemistry, CPIV antigen was demonstrated in tracheal epithelial cells, whereas nasal cavity, bronchi, bronchioles and lung were devoid of viral antigen. Ferrets given CPIV alone developed a minimal lymphocytic tracheitis with minimal loss of cilia and CPIV antigen was observed only 4 days p. i. 17 days p. i., normal epithelial organization and ciliary reappearance was reestablished. Ferrets treated with cyclophosphamide and infected with CPIV exhibited mild to moderate histological lesions as above with similar scanning electron microscopic changes until 36 p. i. Tracheal lesions consisted of intraepithelial and submucosal infiltration of lymphocytes and macrophages, focal epithelial hyperplasia and multifocal loss of cilia. In addition, mild and transient neutrophilic infiltration was observed. In immunosuppressed ferrets, viral antigen expression was prominent and demonstrated 4 and 8 days p. i. These data suggest that ferrets are susceptible to aerosol CPIV infection.

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“…Raw beef was suspected as the source of infection, reinforcing the need to exclude raw meat products from the diet of ferrets used for research. IBR does cause significant respiratory pathology in experimentally infected ferrets (Porter et al, 1975).…”

Section: F Other Virusesmentioning

confidence: 93%

“…Infectious bovine rhinotracheitis (IBR) was isolated from the liver, spleen, and lung of clinically normal ferrets (Porter et al, 1975). Raw beef was suspected as the source of infection, reinforcing the need to exclude raw meat products from the diet of ferrets used for research.…”

Section: F Other Virusesmentioning

confidence: 99%