Isolement bio-dirigé d’un antifongique à partir de Haliclona enamela récoltée du port de Jorf Lasfar, Maroc

El-Wahidi, M.; El-Amraoui, B.; Fassouane, A.; Bamhaoud, Toufiq

doi:10.1016/j.mycmed.2013.04.006

Cited by 3 publications

(4 citation statements)

References 22 publications

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“…The sponge genus Haliclona is known for its high chemical various secondary metabolites with interesting biological activities (Faulkner 2002 ) including the antifungal (Barrett et al 1996 ; Clark et al 2001 ; El-Wahidi et al 2013 ), antileishmanial (Dube et al 2007 ), antioxidant (Regoli et al 2004 ), cytotoxic (Fusetani et al 1989 ) and other activities (Lakshmi et al 2009 ; Randazzo et al 2001 ).…”

Section: Resultsmentioning

confidence: 99%

In vitro screening of antifungal activity of marine sponge extracts against five phytopathogenic fungi

2014

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The aim of our research is the screening of extracts of marine sponges for their antifungal activity against phytopathogenic fungi. The in vitro screening of hydroalcoholic and organic extracts of ten marine sponges from Atlantic coast of Morocco against five phytopathogenic fungi (Fusarium oxysporum f.sp. melonis, Fusarium oxysporum f.sp. radicis-lycopersici, Fusarium oxysporum f.sp. ciceris, Botrytis cinerea and Penicillium digitatum) showed that only two sponges (Haliclona viscosa and Cynachirella tarentina) are active against all phytopathogenic fungi studied.

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Section: Resultsmentioning

confidence: 99%

In vitro screening of antifungal activity of marine sponge extracts against five phytopathogenic fungi

2014

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“…Sphingolipids are already known for their antiseptic and antifungal activity (Bibel et al ., ), and sphingosine and its derivatives are natural antimicrobial agents, protecting the human skin from bacterial colonization (Bibel et al ., , ) as well as being anti‐inflammatory agents (Radhika et al ., ). The Moroccan invertebrates and especially sponges are poorly studied (Rifai et al ., , ; El‐Amraoui et al ., ; El‐Wahidi et al ., ), but are a promising source of new compounds with diverse biological activities (El‐Amraoui et al ., ; El‐Wahidi et al ., ).…”

Section: Discussionmentioning

confidence: 97%

“…; El-Amraoui et al, 2010;El-Wahidi et al, 2011), but are a promising source of new compounds with diverse biological activitiesEl-Wahidi et al, 2013).…”

mentioning

confidence: 99%

Control of postharvest green mould of citrus by haliscosamine isolated from Haliclona viscosa sponge

2014

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The aim of this study was to evaluate the antifungal activity of haliscosamine isolated from Haliclona viscosa sea sponge from the Moroccan Atlantic coast against Penicillium digitatum, the causal agent of citrus green mould. The in vitro antifungal activity of haliscosamine, determined using the agar disc-diffusion method, showed that haliscosamine and DESOGERME SP VEGETAUX â (reference product) have fungicidal activity with inhibition diameters of 19 and 18 mm, respectively. Haliscosamine and a positive control (DESO-GERME SP VEGETAUX â ) were tested in vivo in comparison with a negative control on orange fruits in normal storage conditions. This test showed that after four weeks of storage, the rate of decay of citrus fruits treated with haliscosamine or DESOGERME does not exceed 14%, whereas in the negative control the decay rate is 77%. The results of in vitro and in vivo tests indicate that haliscosamine and DESOGERME SP VEGETAUX â have an important antifungal potential against P. digitatum and that haliscosamine (a natural product) may represent an alternative to the use of chemical fungicides.

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“…Furthermore, Marine sponges are a potential source of new biological compounds with diverse biological activities (Acosta and Rodriguez 1992 ; Baslow and Turlapaty 1969 ; Akiyama et al 2009 ; Bao et al 2007a ; Bao et al 2005 ; Bao et al 2007b ). In Morocco, few studies are carried out about Moroccan sponges with an important biological material for the isolation of new molecule (El Amraoui et al 2014b ; EL Amraoui et al 2014a ; El Amraoui et al 2013 ; El Amraoui et al 2010 ; El-Wahidi et al 2011 ; El-Wahidi et al 2013 ). Haliscosamine isolated from the Moroccan marine sponge Haliclona viscosa is a new derivative of sphingosine with an original molecular structure ((Z)-2-amino-docos-9- ene-1,3,13,14-tetraol) (El Amraoui et al 2013 ).…”

Section: Introductionmentioning

confidence: 99%

Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis

et al. 2015

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Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa. The aim of this study was to test Haliscosamine in vitro and in vivo for its antifungal activity against Fusarium oxysporum f.sp. melonis causing fusarium wilt of melon.Overall, in vitro test showed that haliscosamine has a similar effect as DESOGERME SP VEGETAUX®. In addition, in vivo showed a significant effect against Fusarium oxysporum f.sp. melonis. Taking to gather, our results suggest that haliscosamine constitutes a potential candidate against Fusarium oxysporum f.sp. melonis and the possibility to use in phytopathology.

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Isolement bio-dirigé d’un antifongique à partir de Haliclona enamela récoltée du port de Jorf Lasfar, Maroc

Cited by 3 publications

References 22 publications

In vitro screening of antifungal activity of marine sponge extracts against five phytopathogenic fungi

In vitro screening of antifungal activity of marine sponge extracts against five phytopathogenic fungi

Control of postharvest green mould of citrus by haliscosamine isolated from Haliclona viscosa sponge

Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis

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