“…Despite extensive research on the networks of substance-using populations, our understanding of how risk epidemiology, viral characteristics, and social determinants intersect with networks to shape HIV transmission continues to develop. New research supports the importance of network size [21], structure [22], bridging (i.e., ties connecting different groups) [23], clustering (i.e., nodes grouping together) [24], multiplexity (i.e., ties with multiple social connections, such as a sexual and drug use connection) [25][26][27], and social support and capital [28][29][30] for HIV risk behavior, transmission, viral suppression, HIV disclosure, and ART initiation. This work entails an expanded focus on populations that have historically received less attention, including research on the networks of non-injecting drug users [31,32], substance users in suburban and rural areas [22,31,[33][34][35][36], and the role of networks in newly emerging HIV outbreaks, both domestically [37][38][39] and globally [3,[40][41][42][43].…”