It's Not Your Mother's Marijuana

Warner, Tamara D.; Roussos-Ross, Dikea; Behnke, Marylou

doi:10.1016/j.clp.2014.08.009

Cited by 64 publications

(38 citation statements)

References 87 publications

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“…637," 2015;Jaques et al, 2014;Warner, Roussos-Ross, & Behnke, 2014). Therefore, use of marijuana during nursing is discouraged in the absence of evidence that it is safe for the newborn (Jaques et al, 2014;Warner et al, 2014).…”

Section: Accepted Manuscriptmentioning

confidence: 93%

“…Most professional bodies, including the Academy of Breastfeeding Medicine, recommend against breastfeeding whenever illicit drug use has occurred during the 30-day period before birth or if it is ongoing (Jaques et al, 2014;Warner et al, 2014). However, some professionals argue that, depending on family circumstances, among women who find abstaining from marijuana use to be difficult, the benefits of breastfeeding may outweigh the negative sideeffects of marijuana, even with continued use (particularly in infrequent cannabis users) (Hill & Reed, 2013;Jaques et al, 2014).…”

Section: Accepted Manuscriptmentioning

confidence: 96%

See 1 more Smart Citation

Prenatal, perinatal, and adolescent exposure to marijuana: Relationships with aggressive behavior

Barthélémy

Richardson

Cabral

et al. 2016

Neurotoxicology and Teratology

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Section: Accepted Manuscriptmentioning

confidence: 93%

Section: Accepted Manuscriptmentioning

confidence: 96%

Prenatal, perinatal, and adolescent exposure to marijuana: Relationships with aggressive behavior

Barthélémy

Richardson

Cabral

et al. 2016

Neurotoxicology and Teratology

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“…In utero exposure to cannabis does not typically result in congenital birth defects (Warner et al, 2014, Linn et al, 1983, van Gelder et al 2009) and there is no phenotypic signature of this compound in newborns. Effects on physical growth at birth and during the neonatal period have been reported in some studies (see below) but not others (Bada et al, 2006; Conner et al, 2015; van Gelder et al, 2010).…”

Section: Impact Of Prenatal Cannabis Exposure On Neurodevelopmental Omentioning

confidence: 99%

Cannabis use during pregnancy: Pharmacokinetics and effects on child development

Grant

Petroff

Isoherranen

et al. 2018

Pharmacology & Therapeutics

191

159

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The broad-based legalization of cannabis use has created a strong need to understand its impact on human health and behavior. The risks that may be associated with cannabis use, particularly for sensitive subgroups such as pregnant women, are difficult to define because of a paucity of dose-response data and the recent increase in cannabis potency. Although there is a large body of evidence detailing the mode of action of Δ9‐tetrahydrocannabinol (THC) in adults, little work has focused on understanding how cannabis use during pregnancy may impact the development of the fetal nervous system and whether additional plant-derived cannabinoids might participate. This manuscript presents an overview of the historical and contemporary literature focused on the mode of action of THC in the developing brain, comparative pharmacokinetics in both pregnant and nonpregnant model systems and neurodevelopmental outcomes in exposed offspring. Despite growing public health significance, pharmacokinetic studies of THC have focused on nonpregnant adult subjects and there are few published reports on disposition parameters during pregnancy. Data from preclinical species show that THC readily crosses the placenta although fetal exposures appear lower than maternal exposures. The neurodevelopmental data in human and preclinical species suggest that prenatal exposure to THC may lead to subtle, persistent changes in targeted aspects of higher-level cognition and psychological well-being. There is an urgent need for well-controlled studies in humans and preclinical models on THC as a developmental neurotoxicant. Until more information is available, pregnant women should not assume that using cannabis during pregnancy is safe.

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“…This retrospective cohort study used a large population health registry and controlled for known confounders, such as tobacco smoking, alcohol consumption, and use of other illicit drugs. Cannabis use in pregnancy is also associated with adverse effects on fetal and adolescent brain growth [111], poorer attention and executive functioning skills, lower academic achievement, increased behavioral problems [113]. Of note the effects of marijuana often seen in conjunction with other substances, and are most pronounced in heavy users.…”

Section: Cannabismentioning

confidence: 99%

Substance Use in the Perinatal Period

Forray

Foster

2015

Curr Psychiatry Rep

129

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Perinatal substance use remains a major public health problem and is associated with a number of deleterious maternal and fetal effects. Polysubstance use in pregnancy is common, and can potentiate adverse maternal and fetal outcomes. Tobacco is the most commonly used substance in pregnancy, followed by alcohol and illicit substances. The treatments for perinatal substance use are limited and consist mostly of behavioral and psychosocial interventions. Of these contingency management has shown the most efficacy. More recently, novel interventions such as progesterone for postpartum cocaine use have shown promise. The purpose of this review is to examine the recent literature on the use of tobacco, alcohol, cannabis, stimulants, and opioids in the perinatal period, their effects on maternal and fetal health and current treatments.

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It's Not Your Mother's Marijuana

Cited by 64 publications

References 87 publications

Prenatal, perinatal, and adolescent exposure to marijuana: Relationships with aggressive behavior

Prenatal, perinatal, and adolescent exposure to marijuana: Relationships with aggressive behavior

Cannabis use during pregnancy: Pharmacokinetics and effects on child development

Substance Use in the Perinatal Period

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