Main targets of this activity research are the making and the optimization of new detectors by means of the Systems Engineering methods. With the observation of the gravitational wave event of August 17th, 2017 and then with those of the extragalactic neutrino of September 22nd, the Multimessenger Astrophysics era began. It is a new way of exploring the Universe, powered by globally coordinated observations of several experiments. So, new X and gamma rays’ detectors solutions are needed in order to provide competitive results in the energy range 10 keV–10 meV. Here is briefly described how the Systems Engineering can improve the development of the proposal of a new technique: The Crystal Eye, a wide field of view detector with a good spatial resolution obtained thanks to a high pixelation.