In this paper, we consider the second-order Jacobi differential expressionhere, the Jacobi parameters are α > −1 and β = −1. This is a nonclassical setting since the classical setting for this expression is generally considered when α, β > −1. In the classical setting, it is well-known that the Jacobi polynomials {P (α,β) n } ∞ n=0 are (orthogonal) eigenfunctions of a self-adjoint operator T α,β , generated by the Jacobi differential expression, in the Hilbert space L 2 ((−1, 1); (1 − x) α (1 + x) β ). When α > −1 and β = −1, the Jacobi polynomial of degree 0 does not belong to the Hilbert space L 2 ((−1, 1); (1 − x) α (1 + x) −1 ). However, in this paper, we show that the full sequence of Jacobi polynomials {P (α,−1) n } ∞ n=0 forms a complete orthogonal set in a Hilbert-Sobolev space Wα, generated by the inner productWe also construct a self-adjoint operator Tα, generated by α,−1 [·] in Wα, that has the Jacobi polynomials {P (α,−1) n } ∞ n=0 as eigenfunctions. Mathematics Subject Classification (2010). Primary 33C45, 34B30, 47B25; Secondary 34B20, 47B65. 284 A. Bruder and L. L. Littlejohn Results. Math.