This study combines multi-item Just-in-Time solid transportation problems, budget constraints, and carbon emissions with potential profit maximization. Carbon emissions and other greenhouse gas emissions from various modes of transportation cause air pollution and harmful changes in climate. Realizing the impact of time in real-life transportation problems, here we introduce the Just-in-Time concept that helps to find the optimal network for transporting goods from origin to destination on time. The model of multiitem Just-in-Time solid transportation problem based on carbon emission is formulated, and then an algorithm is developed under some priority-based approaches to obtain an optimal solution. To test and justify the efficiency of the proposed study, we include an example having two-fold priority: (i) first priority is to deliver goods within the scheduled time, and (ii) second priority is to maximize profit. Finally, the article ends with the conclusions and future study.