Joint effect of occupation and nationality on the prevalence of peptic ulcer in German workers.

Sonnenberg, Amnon; Haas, Joanna F.

doi:10.1136/oem.43.7.490

Cited by 7 publications

(5 citation statements)

References 12 publications

(1 reference statement)

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“…But Sonnenberg and Haas have reported higher incidence of gastric and duodenal ulcer and non-ulcer dyspepsia among manual labourers in German population. 9 Majority of our subjects were non vegetarians (83%), but no relation was found between diet and dyspeptic symptoms. Similar results were also obtained in a case control study by Cuperus et al 10 Another case control study from Norway by Lind et al concluded that abdominal symptoms were due to food hypersensitivity.…”

Section: Discussionmentioning

confidence: 99%

Clinical and endoscopic evaluation of dyspeptic patients attending a tertiary care hospital in South India: A prospective study

Manappallil

2017

Asian J Med Sci

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Background:The incidence of dyspepsia has been increasing all over the world; with some having an organic cause while others have functional dyspepsia. Helicobacter pylori infection is also a contributory factor. Moreover, these dyspeptic patients also show a wide spectrum of symptoms. Aims and Objective: The aim of this study was to clinically and endoscopically evaluate the patients with dyspepsia; and also to assess the prevalence of Helicobacter pylori. Materials and Methods: A prospective study was conducted on 100 dyspeptic patients who were advised an upper gastrointestinal endoscopy based on clinical grounds at Pondicherry Institute of Medical Sciences, Pondicherry, India. Results: Of the 100 dyspeptic patients evaluated in this study, the mean age was 42 years, with 54% belonging to 20 to 40 years, 35% to 41 to 60 years and 11% above 60 years age groups. 61% were males and 39% females. They belonged to various occupational groups with majority leading a retired life or as homemakers (36%), followed by those with white collar jobs or as students (29%), unskilled workers (26%) and skilled workers (9%). Majority of these patients were non vegetarians (83%). Smokers and alcoholics comprised of 38% and 43% of the subjects respectively; and 31% had history of NSAID consumption. Epigastric pain and epigastric burning sensation were the main complaints among dyspeptic patients. Heartburn was more common among smokers and alcoholics; and epigastric pain among NSAID users. The main endoscopic abnormalities were erythematous and erosive gastritis (42% and 21% respectively), followed by duodenal ulcer (18%) and erosive duodenitis (15%). Duodenal ulcers were more common among males (89%). Duodenitis (89%) and duodenal ulcers (67%) were mainly seen in alcoholics. 18% of our study patients had a normal endoscopic finding. Helicobacter pylori was present in 35% of the subjects. Epigastric pain and epigastric burning sensation were the main symptoms among these patients; with erythematous gastritis being the main endoscopic finding. Conclusion: Dyspepsia was more common among younger age groups. Epigastric pain and epigastric burning sensation were the most common symptoms. Erythematous gastritis followed by erosive gastritis was the common endoscopic abnormality. Some patients also had normal findings on endoscopy.Helicobacter pylori was present in a significant number of patients.

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Section: Discussionmentioning

confidence: 99%

Clinical and endoscopic evaluation of dyspeptic patients attending a tertiary care hospital in South India: A prospective study

Manappallil

2017

Asian J Med Sci

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“…It has also been suggested that the high prevalence among migrant workers reflects their current predominance in physically demanding jobs, and that the secular decline in incidence of peptic ulcer may be linked to a progressive reduction in average energy expenditures at work [44].…”

Section: Occupational Activitymentioning

confidence: 99%

Peptic Ulcer and Exercise

Shephard

2016

Sports Med

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Relationships between peptic ulcer and physical activity have as yet received little attention. The prevalence of ulceration is high in racehorses and sled dogs, particularly during periods of competition. In humans, some occupational comparisons show an increased risk among manual workers, but it remains difficult to separate effects of work-related activity from social class and attendant influences of smoking, excessive alcohol consumption, shift work, and other stressors. Two studies of leisure activity point to some benefit from moderate physical activity, one finding a reduced risk of gastric ulcers and the other finding no effect on gastric ulcers but a reduced risk of duodenal ulcers in men only. Moderate physical activity could have a favorable impact on a number of risk factors for peptic ulceration. It could reduce gastric secretions and enhance immune function, with the latter reducing the risk of Helicobacter pylori infection. Moderate activity might also reduce anxiety and encourage the adoption of a healthy lifestyle, with avoidance of smoking and an excessive consumption of alcohol. However, prolonged endurance exercise seems likely to have a negative impact, suppressing immune function, reducing mucosal blood flow, and calling for frequent administration of non-steroidal anti-inflammatory drugs (NSAIDs). As with other aspects of exercise medicine, there may be a J-shaped relationship between dose and response. Limited human observations suggest a favourable response to bouts of moderate leisure activity but little benefit from heavy occupational activity and, in some animal studies, negative effects at high volumes and intensities of exercise. Further research is recommended to confirm the nature of this relationship, clarify the location of any nadir of risk for various classes of individual, and to explore mechanisms and antidotes.

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“…It is now recognised that those deprived in childhood (for example living with poor sanitation or family overcrowding) have the highest H. pylori infection risk. [11][12][13][14][15][16] As socio-economic conditions improved in Western societies in the 20th century, so too the prevalence and mortality of PUD declined, with changes related to the period of birth. [17][18][19][20] The declining numbers of operations observed in York in successive decades suggests this too is a birth cohort effect.…”

Section: The Decline In Psmentioning

confidence: 99%

The scars of time: the disappearance of peptic ulcer-related pyloric stenosis through the 20th century

Hall

Royston²,

Bardhan³

2014

J R Coll Physicians Edinb

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Joint effect of occupation and nationality on the prevalence of peptic ulcer in German workers.

Cited by 7 publications

References 12 publications

Clinical and endoscopic evaluation of dyspeptic patients attending a tertiary care hospital in South India: A prospective study

Clinical and endoscopic evaluation of dyspeptic patients attending a tertiary care hospital in South India: A prospective study

Peptic Ulcer and Exercise

The scars of time: the disappearance of peptic ulcer-related pyloric stenosis through the 20th century

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