Joshanda: A Traditional Herbal Approach for Treatment of Respiratory Catarrh

Ahuja, Vijay; Gulati, Monica; Lakhanpal, Sorabh; Goswami, Manish; Ahmad, Saheem

doi:10.2174/157339809788190011

Cited by 4 publications

(1 citation statement)

References 65 publications

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“…Joshanda, a traditional antitussive preparation consisting of seven plant ingredients has been used in the Unani system of medicine for centuries (Ahuja et al, 2009). The word "Joshanda" is derived from two words i.e.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial, antitussive, antioxidant and toxicological evaluation of Joshanda Lozenges

Bansal¹,

Gulati²,

Singh³

et al. 2015

J App Pharm Sci

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Joshanda, a Greco-urban formulation comprising seven herbs has been used since centuries for the treatment of cold, cough and associated allergic reactions. Conventionally, it is used in the form of an extemporaneously prepared decoction. However, in the current scenario, lozenges happen to be the dosage form of choice for antitussive drugs. In case of polyherbal drugs, the dosage form assumes a great importance in order to ensure that all the phyto-components exert their pharmacological effect to the maximum. Based on the popularity of lozenges, conventional decoction form of Joshanda was formulated in the form of lozenges. Lozenges were evaluated for routine quality control tests. The most remarkable feature of the formulation was that excellent compression, hardness, friability and disintegration properties could be achieved without the addition of any external binder. The prepared formulation was subjected to in vitro antioxidant activity, antibacterial activity against common respiratory tract pathogens, in vivo antitussive activity and acute toxicity studies using Albino Wistar mice. Accelerated stability studies were conducted as per ICH guidelines. The performance of lozenges was found to be satisfactory in all the tested aspects. Our study proposes the use of lozenges as a preferred dosage form of the conventionally used decoction of Joshanda.

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Section: Introductionmentioning

confidence: 99%

Antibacterial, antitussive, antioxidant and toxicological evaluation of Joshanda Lozenges

Bansal¹,

Gulati²,

Singh³

et al. 2015

J App Pharm Sci

Self Cite

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Chemical and pharmacological comparison of modern and traditional dosage forms of Joshanda

Parveen

Bukhari

Shehzadi

et al. 2017

Natural Product Research

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Recently, a traditional remedy (Joshanda) has been replaced largely by modern ready-to-use dosage forms, which have not been compared to the original remedy. Therefore, the present study aimed to compare a number of modern dosage forms with traditional remedy. Seven brands, 3 batches each, were compared with a Lab-made formulation with reference to analytical (proximate analyses, spectroscopic and chromatographic metabolomes) and pharmacological profiles (anti-inflammatory and antibacterial activities). Chemical and pharmacological differences were found between Lab-made Joshanda and modern dosage forms. Such variations were also found within the brands and batches of modern formulations (p < 0.05). The Lab-made Joshanda showed significantly higher pharmacological activities as compared to modern brands (p ). The results of the present study indicate that modern dosage forms are unstandardised and less effective than the traditional remedy. Characteristic profiles obtained from Lab-made Joshanda may be used as reference to produce comparable dosage forms.

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A Review on the Phytochemistry, Ethnobotanical Uses and Pharmacology of Borago Species

Ramezani

Amiri

Zibaee

et al. 2020

CPD

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Ethnopharmacological Relevance: Borago L., (family Boraginaceae) is a small genus of annual or perennial herbs with branched flowers, which is commonly found in the Mediterranean region. Some species known as Gavzabȃn in Asian and some African countries are traditionally used instead of Borago. Aims of the Review: The purpose of this study was to provide comprehensive scientific information on phytochemistry, traditional uses and pharmacological activities of Borago species to provide an insight into further research on the therapeutic potential of these plants. In many studies, it has been shown that different parts of Borago species, including leaves, flowers, seeds, roots and aerial parts possess numerous ethnobotanical values. Materials and Methods: All ethnobotanical, phytochemical, pharmacological, and clinical data were collected from online journals, magazines and books (all of which were published in English, Arabic, and Persian) from 1968 to 2018. Electronic databases such as Google, Google Scholar, PubMed, Science Direct, Researchgate, and other online collections were used. Results: The phytochemical studies on five species showed a wide range of phytochemicals belonging to different classes of secondary metabolites. From a pharmacological point of view, different extracts and fractions, essential oils, and pure compounds isolated from various Borago species have shown diverse activities in in vitro, in vivo, and clinical studies confirming various traditional uses of Borago genus. Conclusions: Considering the reported activities of the Borago genus both in traditional and modern medicine, further studies on biological aspects and identification of the mechanism of action for drug discovery are highly required.

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Joshanda: A Traditional Herbal Approach for Treatment of Respiratory Catarrh

Cited by 4 publications

References 65 publications

Antibacterial, antitussive, antioxidant and toxicological evaluation of Joshanda Lozenges

Antibacterial, antitussive, antioxidant and toxicological evaluation of Joshanda Lozenges

Chemical and pharmacological comparison of modern and traditional dosage forms of Joshanda

A Review on the Phytochemistry, Ethnobotanical Uses and Pharmacology of Borago Species

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