This study investigates the effect of the partial replacement of ordinary Portland cement (OPC) with cement kiln dust (CKD) on the engineering properties of pozzolanic concrete for use in block manufacturing. Ultimately, this could potentially reduce cement consumption and CO2 emissions. The study was carried out on cylindrical concrete samples prepared from five mixtures comprising 71.13% pozzolan and 14.16% water, with 0, 5, 10, 15, or 20% of the OPC fraction (14.71 wt.%) replaced by CKD. The samples were tested for density and compressive strength (UCS) at curing ages of 7, 14, 28, 56, and 91 days; and for voids and water absorption after 28 curing days. Results show that increasing CKD content lowered the voids and increased the water absorption. The 15% CKD sample had the highest UCS, regardless of the curing age. X-ray diffraction analysis confirmed that the phase responsible for hydration, calcium silicate hydrate, was higher in the 15% CKD sample than the control.