Juvenile Gigantomastie. Ein Fallbericht und Literaturübersicht

Abstract

A juvenile gigantomastia with wet tender ulceration in a 13-year-old premenarchal girl (155 cm, 51 kg) developed in only 6 months. Treatment consisted of a bilateral reduction mammoplasty with free transplantation of the areolae and nipples and the removal of 4.2 kg of breast tissue. Macroscopically the resections consisted of "white and solid" tissue. Histologically a fibrous-cystic mastopathia was confirmed. It is thus suggested that the etiology of this disease might be related to a local hypersensitivity to estrogen. Mediactions (Tamoxifen) are mostly ineffective. The treatment consisted of reduction plasty.

Giant Breast Hypertrophy in Juvenile: A Rare Case

“…The treatment modalities in JHB involve the following four strategies: (1) surgical management, (2) medical therapy administered either preoperatively or (3) postoperatively, and (4) medical therapy alone [5,7]. In this case, mammoplasty reduction of right breast reduction was successfully performed.…”

“…Breast reduction surgery is ideal and offers improvement with those problems mentioned above. The management of this disease includes hormonal interventions, surgery, and a combination to prevent recurrence [7].…”

Bilateral Breast Enlargement and Reddish Skin Macules as First Signs of Acute Lymphoblastic T Cell Leukemia

“…Differential diagnoses include idiopathic gigantomastia, which histopathologically presents as a fibrocystic mastopathy, and pseudoangiomatous stromal hyperplasia [19,20]. The pathogenesis of both diseases is unclear and comprises sporadic and familiar occurrence [21,22]. Further, autoimmune diseases, e.g.…”

Juvenile gigantomastia, two cases treated by reduction mammoplasty with nipple-areola complex graft

“…[1] Symptoms of gigantomastia are ranging from pain to necrosis or sepsis. [6] It may include mastalgia (breast pain) , [10] ulceration and infection, [2,11] G orthopnea, [3] posture problems, [10,12] scoliosis, kyphosis or lordosis [3,13] and back pain, [3] chronic traction injury to 4th/5th/6th intercostals nerves with resultant loss of nipple sensation [6] and hygienic difficulties, intertriginous lesions at the inframammary folds . [3] Investigations to be done in addition to hormonal study include thyroid hormones and magnetic resonance imaging [MRI] of the brain to rule out enlargement of sella turcica and hypophysial enlargement; ultrasound of the breasts and abdomen, to exclude any disorder of breasts, and abdomen.…”