Juvenile laryngeal papillomatosis

Irwin, Bradley; Hendrickse, William; Pincott, J. R.; Bailey, C. M.; Evans, John N.

doi:10.1017/s002221510009945x

Cited by 33 publications

(19 citation statements)

References 32 publications

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“…By contrast, in the juvenile onset group most of the cases were female, and this was was also found by Irwin et a1. 16 However, this finding is not supported in other and bigger series.I7, Analysis of our male/female ratio with respect to age (adult or juvenile onset) does show a significant sex difference with respect to age (xz=0.54, P<O.Ol, IDF).…”

Section: Discussionmentioning

confidence: 81%

Laryngeal papillomatosis: analysis of 113 patients

Quiney¹,

Hall²,

Croft³

1989

Clin Otolaryngol

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Despite the low incidence of these diseases, both juvenile onset and adult onset laryngeal papillomatosis continue to concern otolaryngologists because treatment is often prolonged and unsatisfactory. Over many years various treatments have met with varied claims of success, yet no treatment today is universally accepted. We review the underlying clinical problems, the presentation, the treatment and eventual outcome of 113 patients seen at this hospital over the last 20 years with laryngeal papillomatosis. Using multivariate analysis of age at presentation, sex, smoking habits, initial site of disease, frequency of treatment and eventual outcome, two distinct patterns are revealed both between juvenile and adult onset disease and between male and female patients. Single-site lesions in adults have the best prognosis. Female children with multiple confluent lesions at presentation have the worst prognosis.

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Section: Discussionmentioning

confidence: 81%

Laryngeal papillomatosis: analysis of 113 patients

Quiney¹,

Hall²,

Croft³

1989

Clin Otolaryngol

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“…The first peak of recurrent respiratory papillomatosis occurs at less than 5 years of age, with approximately 25% of these cases presenting during infancy. The second peak occurs between the ages of 20 and 30 years 14,17–19 . In the USA, there are 2300 new cases among children and 3600 new cases among adults diagnosed each year, with an incidence of 4.3 and 1.8 per 100 000 respectively.…”

Section: Epidemiologymentioning

confidence: 99%

“…The goals of surgical resection are to eradicate disease and assure an adequate airway, improve the voice, and facilitate disease remission while limiting morbidity 43 . Out of historical interest, the following treatment modalities have been used and include cryosurgery, 6 suction diathermy, 18 and ultrasonography 44 . Currently, surgery using cold steel, CO 2 laser and laryngeal shaver blade are the most common surgical techniques.…”

Section: Treatmentmentioning

confidence: 99%

“…The second peak occurs between the ages of 20 and 30 years. 14,[17][18][19] In the USA, there are 2300 new cases among children and 3600 new cases among adults diagnosed each year, with an incidence of 4.3 and 1.8 per 100 000 respectively. Boys and girls appear to be nearly equally affected in juvenile-onset recurrent respiratory papillomatosis [20][21][22] in contrast with adult-onset recurrent respiratory papillomatosis, which is a disease transmitted via sexual contact or via indirect contact with ano-genital lesions, preferentially affecting men by a ratio of approximately 3:2 21,23,24 Interestingly, nearly 75% of affected children are first-born.…”

Section: Historymentioning

confidence: 99%

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Recurrent respiratory papillomatosis

2002

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Recurrent respiratory papillomatosis is a relatively rare disease caused by members of the human papilloma virus family. Lesions may occur anywhere throughout the respiratory tract but show a predilection for squamo-columnar epithelial junctions, frequently leading to hoarseness and upper airway obstruction. Rarely, it can progress to squamous cell carcinoma. The impact of recurrent respiratory papillomatosis on patients, their families, and the health care system is considerable. Unfortunately, despite extensive investigational studies, no cure is available for the disease. This article reviews the aetiology of and therapeutic options for recurrent respiratory papillomatosis.

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“…potential seeding of papillomas to the distal airway. Inhalation induction with oxygen and halothane allows assessment of ease of ventilation temporary (14,15). Adjuvant treatment to surgical resection with induction of anaesthesia.…”

Section: Introductionmentioning

confidence: 99%

Juvenile laryngeal papillomatosis: scary anaesthetic!

Theroux

Grodecki

Reilly

et al. 1998

Pediatric Anesthesia

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We describe three children ages 20 to 33 months who presented for surgical resection of their laryngeal papillomata. Their anaesthetic management revealed the severity of obstruction which these children presented and the obstacles that faced the anaesthesiologist trying to secure the airway and provide adequate ventilation. The airway obstruction had both a fixed and a dynamic component to it. This was evidenced by the ability of the children to maintain ventilation when spontaneously breathing. But, they exhibited total obstruction when ventilation was attempted via mask using positive pressure. It is possible to encounter obstruction to ventilation after the trachea has been intubated because of papillomata that were 'shaved off,' filling the tracheal tube lumen.

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Juvenile laryngeal papillomatosis

Cited by 33 publications

References 32 publications

Laryngeal papillomatosis: analysis of 113 patients

Laryngeal papillomatosis: analysis of 113 patients

Recurrent respiratory papillomatosis

Juvenile laryngeal papillomatosis: scary anaesthetic!

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