Juxtaposition of somatostatin cell and parietal cell in the dog stomach.

The relative frequency and topographical distribution of somatostatin-, GRP-,APP-, glucagon-,5-HT-, and neurotensin-immunoreactive cells in the proventriculus of seven species of birds.

“…These morphological features support the concept that many of the proventricular endocrine cells may function as mechanoreceptors and respond to mechanical stimuli such as pressure or tension caused by foods (KUSUMOTO et al, 1979;LARSSON et al, 1979;YAMADA et al, 1979). Somatostatin-immunoreactive cells in particular may function as mechanoreceptors as well as typical paracrine cells as reported in mammalian fundic glands (ALUMETS et al, 1979;KUSUMOTO et al, 1979;LARSSON et al, 1979).…”

“…These morphological features support the concept that many of the proventricular endocrine cells may function as mechanoreceptors and respond to mechanical stimuli such as pressure or tension caused by foods (KUSUMOTO et al, 1979;LARSSON et al, 1979;YAMADA et al, 1979). Somatostatin-immunoreactive cells in particular may function as mechanoreceptors as well as typical paracrine cells as reported in mammalian fundic glands (ALUMETS et al, 1979;KUSUMOTO et al, 1979;LARSSON et al, 1979). It is well established that somatostatin suppresses the secretion of endocrine as well as exocrine cells (PATEL et al, 1981) and that GRP (or bombesin) stimulates both directly and indirectly (via gastrin cells) gastric acid secretion by oxyntic cells (VARNER et al, 1981).…”

The microanatomy of human islets of Langerhans, with special reference to somatostatin (D-) cells.

“…Here, similar processes have been interpreted as the morphologic counterpart of possible cell-to-cell (paracrine) interactions between D-cells and adjacent endocrine and non-endocrine epithelial cells (ALUMETS et al, 1979;KUsuMoTo et al, 1979;LARSSON et al, 1979). Taking into account our findings in islet D-cells, the relationship of gastric D-cell processes to the subepithelial vascular system should also be examined.…”

Immunocytochemical Study of the Gastroenteropancreatic Endocrine Cells of the Sheep

“…Previous reports substantiated the occurrence of some somatostatin-immunoreactive cells with possible paracrine mode of action because they possess long pro cesses that appear to attach to neighboring cells as in the rat [1, 14. 26], dog [22], cat [21], mink [20] and chicken [10], In the sheep, similar cells were detected in the pyloric region. This finding further supports the hypothesis that somatostatin-immunoreactive cells probably act selectively in a paracrine fashion by direct cell-to-cell contacts [14].…”