Kadar 25(OH)D3 darah pada penderita obesitas

Abstract

Blood level 25(OH)D3 in obese peopleBackground: Currently, obesity is a world problem, even the World Health Organization (WHO) declared obesity to be a global epidemic and contributes 5% of global deaths in 2015. Recently, many studies have reported an association between vitamin D levels and the incidence of obesity, although the exact mechanism raises many questions. Objective: This study is to examine the correlation between levels of 25(OH)D3 and body mass index (BMI).Methods: The design of this research is an analytic survey with a case control approach. The population of this study was all students of the Faculty of Medicine, Malahayati University, Bandar Lampung. The number of samples in this study were 60 samples with details of 30 case samples (obesity) and 30 control samples (no obesity). The sampling technique used was purposive sampling. The data used are primary data from direct measurement results. The data were analyzed using the correlation test.Results: The results showed that only one sample had normal 25(OH)D3 levels, while most (more than 98%) had low and very low levels of 25(OH)D3. The correlation test showed that there was a significant relationship between 25(OH)D3 levels with BMI (p=0.008; r= -0.0338), gender (p=0.001; r= -0.457), and total cholesterol levels (p=0.009); r= -0,391).Conclusions: There is a relationship between levels of 25(OH)D3 with BMI, the lower the 25(OH)3 blood level, the higher the risk of increasing BMI. Further research is still needed to ensure that giving vitamin D to obese populations can reduce body weight or BMI.

ANALYSIS OF VITAMIN D LEVELS & COMPLETENESS OF COVID-19 VACCINE WITH RECURRENT COVID-19 INFECTIONS

“…Changes in sun avoidance behavior, such as wearing long clothing, using sunscreen lotion, and indoor activities, are the contributing factors. Several previous studies have also reported a deficiency in vitamin D levels, both in adolescents and the elderly 23,24 . Similarly, the results show the same pattern, with a very small number of samples having levels within the normal range 25,26 .…”

“…to be continuously promoted to ensure that these levels remain within the normal range 36 . Outdoor activities should be encouraged to maximize exposure to UVB rays, allowing the biosynthesis in the skin to function properly 37 and preventing various diseases associated with the deficiency 23,38,39 .…”

Analysis Of Vitamin D Levels in The Population Infected with Covid-19

“…Intake of foods/drinks that contain lots of vitamin D, such as fish, fish oil, eggs and milk (Statsenko et al, 2022) and outdoor activity patterns need to be optimized so that blood levels of vitamin D are within normal ranges (De Rui et al, 2014). Outdoor activities must continue to be encouraged to optimize UVB exposure so that the vitamin D biosynthesis process in the skin runs well (Hall, 2015) and can avoid several diseases known to be associated with low levels of vitamin D in the blood (Hermawan & Hidayat, 2022;Hermawan, Muhani, & Arisandi, 2022;Hermawan & Widodo, 2021).…”

Association between 25(OH)D3 Levels and the Presence of COVID-19 Symptoms

“…Previous studies have also reported that there is a deficiency in vitamin D levels both in adolescence and old age. 8,33 There were 31.9% and 70.2% of the subjects that have not completed COVID-19 vaccination and were not compliant in implementing the health protocol, respectively. These results corroborate the results of another research which reports that preventive measures are still low.…”

“…It is known that vitamin D plays an important role in regulating bone and tooth mineralization, as well as preventing various degenerative diseases, such as cancer, heart disease, hypertension, obesity, stroke and diabetes mellitus. [8][9][10][11][12][13][14][15] Many important functions of vitamin D have been reported. However, vitamin D deficiency is a problem reported worldwide.…”