Kahramanmaraş İlindeki Paliurus spina-christi Mill. Bitkisinin Antimikrobiyal ve Antioksidan Aktivitelerinin Araştırılması

Kaya, Elife

doi:10.18016/ksutarimdoga.vi.835763

Cited by 5 publications

(2 citation statements)

References 23 publications

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“…The radical scavenging activity of the investigated samples is higher than that reported for the water and ethanolic extracts from P. spina-christi fruits and leaves collected in Turkey, as the highest inhibition percentages for these samples was about 87.4% at the tested concentration of 800 µg/mL [9].…”

Section: Antioxidant Potentialcontrasting

confidence: 62%

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Molecular Docking Studies and In Vitro Activity of Paliurus spina-christi Mill Extracts as Pancreatic Lipase Inhibitors

Grande,

Marrelli,

Amodeo

et al. 2024

Antioxidants

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Obesity is a risk factor for the onset of chronic diseases. One of the most promising approaches to treating obesity consists of reducing dietary fat absorption using extracts from plants because they contain phenolic compounds, especially flavonoids. Paliurus spina-christi, belonging to the Rhamnaceae family, is one of the five species belonging to the Paliurus genus. Herein, the aerial parts of the plant were extracted with methanol through the pressurized cyclic solid-liquid extraction using the Naviglio extractor ®. The extracts were analyzed with High Performance Thin Layer Chromatography and investigated for their in vitro biological potential. The phytochemical analysis revealed that rutin has been shown to be the most abundant flavonoid component. The best antiradical activity was observed for the fruit extract with an IC50 value of 53.41 ± 1.24 µg/mL. This extract also has a better inhibitory capacity on lipid peroxidation evaluated at a different time of incubation. Potent lipase inhibitor activity of the extract from fruits was also demonstrated with in vitro experiments. This property can be attributed to a direct interaction of main components of P. spina-christi extract with the human pancreatic enzyme as demonstrated by the results of molecular docking experiments conducted on the crystallographic structures of lipase.

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Section: Antioxidant Potentialcontrasting

confidence: 62%

“…A number of studies have demonstrated several biological properties of this plant including antimicrobial, antioxidant, anti-inflammatory and enzyme inhibition [9][10][11][12], antidiabetic [13] and cytotoxic against breast cancer activity [14].…”

Section: Introductionmentioning

confidence: 99%

Molecular Docking Studies and In Vitro Activity of Paliurus spina-christi Mill Extracts as Pancreatic Lipase Inhibitors

Grande,

Marrelli,

Amodeo

et al. 2024

Antioxidants

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Investigation of antimicrobial and antioxidant activities of Chenopodium album extracts and their effects on gentamicin nephrotoxicity in rats

Akbaş,

Kaya,

Makav

et al. 2023

Food Science & Nutrition

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This study aims to examine the antimicrobial and antioxidant activities of the aerial parts of Chenopodium album extracts (CAE) prepared with different solvents, and how C. album ethanol extract protects them against gentamicin‐induced nephrotoxicity. Extracts of C. album aerial parts were obtained from ethanol, water, methanol, chloroform, and hexane solvents. Thirty‐two male Wistar albino rats were used and gentamycin‐induced nephrotoxicity was utilized as a model. The water extract of C. album exhibited no antimicrobial effect, whereas the methanol one created the highest zone diameter on Bacillus cereus (26 mm). The methanol extract displayed the highest activity in DPPH and ABTS. The ethanol extract yielded the highest reducing power in the CUPRAC. The water extract had the highest reducing power in the FRAP. Concerning gentamicin‐induced renal damage, creatinine and urea levels in the blood were statistically higher in the gentamicin‐C. album group compared to the other groups (p < .05). Urea and creatinine levels of the gentamicin‐C. album group dropped significantly, indicating that the C. album was effective against renal damage. The sections from kidney tissues in the gentamicin + C. album group mostly exhibited mild glomerular congestion. Hyaline cast, cytoplasmic vacuolization, necrosis, and apoptosis were not observed. Thanks to C. album treatment, the gentamicin + C. album suffered less histopathological damage than the gentamicin group did. The results of the present study suggest that CAE can be used as a supportive treatment in people undergoing treatment for nephrotoxicity.

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Investigation the Effects of Jerusalem Thorn (Paliurus spina-christi Mill.), Oriental Hackberry (Celtis tournefortii L.) Fruits and Black Cumin (Nigella sativa L.) Seed on Microbial Quality and Physicochemical Properties of Meatballs

Aydemi̇r

Arslan

2023

Harran Üniversitesi Veteriner Fakültesi Dergisi

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This study aim, was conducted to examine the effect of jerusalem thorn (Paliurus spina-christi Mill./PSC) and oriental hackberry (Celtis tournefortii L./CT) fruits and black cumin (Nigella sativa L./NS) seed on the microbial quality and physicochemical properties during the storage of meatballs +4oC. For this purpose, groups were formed by adding 2% PSC and CT fruits and NS seed to the meatballs. Prepared meatball samples were covered with stretch film in polyethylene plates and stored at 4±1 °C for 16 days. Analyzes were made on the 0, 4, 8, 12 and 16th days of storage in the meatball samples. The pH values of the meatball samples were determined between 5.89-6.02 on day 0, and between 6.10-6.49 on the on day 16, aw values between 0.956-0.964 on day 0 and 0.971-0.980 on day 16. TMAB, psychrotrophic, LAB and yeast-mold counts of meatball samples were 5.14-5.53, 4.62-4.83, 5.04-5.32 and 3.40-3.87 log10 cfu/g, respectively on day 0, and 7.01-7.9, 7.64-8.24, 7.59-8.05 and 5.69-6.27 log10 cfu/g, respectively on day 16. PSC and CT fruits and NS seed slowed down the microbial growth rate in meatballs. The best antimicrobial effect was found in psychrotrophic bacteria for CT fruit and in LAB and yeast-mold for NS seed. As a result, it can be recommended to use PSC, CT fruits and NS seeds in compositions to extend the shelf life of meatballs. The results of this study can provide useful information for anyone dealing with food and further studies investigating the shelf life of meat and meat products.

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Kahramanmaraş İlindeki Paliurus spina-christi Mill. Bitkisinin Antimikrobiyal ve Antioksidan Aktivitelerinin Araştırılması

Cited by 5 publications

References 23 publications

Molecular Docking Studies and In Vitro Activity of Paliurus spina-christi Mill Extracts as Pancreatic Lipase Inhibitors

Molecular Docking Studies and In Vitro Activity of Paliurus spina-christi Mill Extracts as Pancreatic Lipase Inhibitors

Investigation of antimicrobial and antioxidant activities of Chenopodium album extracts and their effects on gentamicin nephrotoxicity in rats

Investigation the Effects of Jerusalem Thorn (Paliurus spina-christi Mill.), Oriental Hackberry (Celtis tournefortii L.) Fruits and Black Cumin (Nigella sativa L.) Seed on Microbial Quality and Physicochemical Properties of Meatballs

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