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Abstract

ABSTRACT:Nelumbo nucifera Gaertn a perennial aquatic plant also known as sacred lotus. The Rhizome, flower, seeds and leaves all are edible and have been proved for their medicinal value. Study about its phyto-nutrients in the aerial parts are scanty. In the present study a phytoscreening of aerial parts of Nelumbo nucifera seeds and seed pod was done to assess and compare their phytoconstituents. Total phenolic content in Nelumbo nucifera seed pod was 93.45mg Gallic Acid Equivalents and 10.5mg/g in the seeds, the total flavonoid content was 295.312mg/g Quercetin Equivalents in NN seedpod and 28.125mg/g in the seeds, tannin content is 508.7mg/g Tannin Equivalents in Nelumbo nucifera seedpod and 69.637mg/g in seeds. Gallic acid, Quercetin and Tannin Equivalents were taken as standard for phenol, flavonoid and tannin content respectively. Phytochemical constituents analyzed by Gas Chromatography -Mass Spectrometry analysis of aerial parts Nelumbo nucifera can be used for routine quality control analysis. The data obtained emphasize, the potential of traditional medicine Nelumbo nucifera, whose phytoconstituents form a source of natural antioxidant which could prevent many free radical mediated diseases.

Flavonoids from Nelumbo nucifera Gaertn., a Medicinal Plant: Uses in Traditional Medicine, Phytochemistry and Pharmacological Activities

“…Lee et al were the first to report on the potential N. nucifera leaves extract to inhibit vascular endothelial growth factor-induced angiogenesis using both in vitro and in vivo models [5]. Yang et al also evaluated the anti-cancer effect of the flavonoids from N. nucifera leaves extracts (i.e., mainly FOGs) using human MCF-7 cell line and in vivo study using a xenograft nude mouse model [44]. Their results evidenced the anti-proliferative action of the flavonoids from N. nucifera leaf extracts on of breast cancer in both in vitro and in vivo models [44].…”

“…Yang et al also evaluated the anti-cancer effect of the flavonoids from N. nucifera leaves extracts (i.e., mainly FOGs) using human MCF-7 cell line and in vivo study using a xenograft nude mouse model [44]. Their results evidenced the anti-proliferative action of the flavonoids from N. nucifera leaf extracts on of breast cancer in both in vitro and in vivo models [44]. In addition, Wu et al investigated the potential of N. nucifera leaves extract on breast cancer metastasis using both in vitro MDA-MB-231 and 4T-1 breast cancer cells and in vivo mice model through PKCα targeting [17].…”

“…Because of the beauty of its flower, it is also the national flower of India and Vietnam. Besides these considerations, there are also many advantages provided by this plant species such as being an ingredient for preparing various cuisines (such as its edible perianth, rhizomes and seeds) and also the important component for traditional medicines or herbal drugs [2,5,6,7,8,9], this latter point being the subject for many studies on phytochemical characterization and/or their bioactivities on this medicinal species, especially the leaves [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44]. The present work highlights and updates on the comparative analysis of flavonoids and compositions in different organs of N. nucifera with an overview of main pharmacological activity from its flavonoid compounds.…”