KAJIAN DRUG RELATED PROBLEMs PENGGUNAAN  ANTIBIOTIK PADA PASIEN PEDIATRIK  DI RSUD KOTA SEMARANG

Timur, Willi Wahyu; Hakim, Lukman; Rahmawati, Fita

doi:10.31603/pharmacy.v3i2.1744

Cited by 2 publications

(4 citation statements)

References 4 publications

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“…Birarra et al 13 reported that the incidence of drug interaction in pediatric ward of Zewditu Memorial Referral Hospital, Addis Ababa, Ethiopia is 38.6%. Whereas a study in District General Hospital in Semarang, Central Java, it was reported as much as 42.32% 18 and another study conducted in District General Hospital and Muhammadiyah Private Hospital in Yogyakarta was 56.4%. 3…”

Section: Drug Interactionsmentioning

confidence: 85%

“…Abrogoua et al 20 reported that the noncompliance at a pediatric unit in Cote d'Ivoire is 24.1%. Whereas, studies conducted by Arfania et al 3 and Timur et al 18 found that non-compliance of antibiotic use among pediatric patients are 1.28 and 9.88%, respectively.…”

Section: Therapy Without Indicationmentioning

confidence: 92%

“…1 The use of antibiotics that are not properly indicated can have the effect of increasing resistance and poor health outcomes. 24 Timur et al 18 reported that there are 5 (6.4%) events of antibiotic therapy without indication in the study conducted in the District General Hospital, Semarang. Pediatric patients with a diagnosis of fever received cefotaxime or ceftriaxone without clear indications.…”

Section: Therapy Without Indicationmentioning

confidence: 98%

“…A study concerning the use of antibiotics in pediatric patients in District General Hospital, Semarang reported that among 28% of patients experiencing DRPs in the form of underdose. 18 Whereas a study in Brazil concerning the use of antibiotics in children in general hospitals found that 12% of the incidence of DRP underdose. If the use of the drug is below the dose and the effect does not achieve the best results, the patient will be dissatisfied and stop taking the drug.…”

Section: Underdosementioning

confidence: 99%

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Drug-related problems (DRPs) on antibiotic therapy in pediatric patients: a review

Titami

Mende

2022

IJPTher

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Drug-related problems are event that can interfere with the outcome of therapy. DRP causes death, morbidity and increases the cost of treatment. Medication errors in pediatrics are common and can increase the risk of harm. Pharmacokinetics and pharmacodynamics of drugs in children will affect drug choice, dosage, dosage form, and dosing interval. Antibiotics are drugs that are often prescribed to pediatric. Based on review, dosing errors were the most common DRP in pediatric antibiotic therapy. Other DRPs that have the potential to occur in pediatric antibiotic therapy include inappropriate drug use, adverse drug reactions, drug interactions, and non adherence. The risk factors for DRPs are age, comorbidities, length of treatment, and the number of drugs. The presence of DRPs in pediatric antibiotic therapy can increase the risk of antibiotic resistance, increase treatment costs, and can affect treatment outcomes. The information in this article is expected to provide information related to the category of DRPs antibiotic therapy that is often used in pediatrics, and can be used as initial data for preventing DRPs and for further research.

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Section: Drug Interactionsmentioning

confidence: 85%

Section: Therapy Without Indicationmentioning

confidence: 92%

Section: Therapy Without Indicationmentioning

confidence: 98%

Section: Underdosementioning

confidence: 99%

See 2 more Smart Citations

Drug-related problems (DRPs) on antibiotic therapy in pediatric patients: a review

Titami

Mende

2022

IJPTher

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Drug-related problems of antibiotic use in gastroenteritis related to patient therapy outcomes at Universitas Gadjah Mada Hospital

Kurniawati

Yasin

Aulia

et al. 2021

Journal of Basic and Clinical Physiology and Pharmacology

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Objectives Gastroenteritis is a disease of digestive system commonly occur among the people. Some cases of gastroenteritis are caused by bacteria, so it is treated by using antibiotics. Inappropriate use of antibiotics can be associated to Drug-Related Problems (DRPs). This study aims to identify patterns of potential DRPs of antibiotic use and analyze the effect of potential DRPs of antibiotic use toward the patient’s therapeutic outcomes and length of stay. Methods This is a retrospective cross-sectional study carried out by using patient’s medical record. The study population was gastroenteritis patients at the inpatient ward of Universitas Gadjah Mada Hospital during January 2018–June 2019. Then, SPSS was employed to analyze the data and the effect of potential DRPs toward therapeutic outcomes was analyzed by utilizing the chi-square method. Results More than half of gastroenteritis patients in Universitas Gadjah Mada Hospital were identified to have potential DRPs of antibiotic use. The most identified of potential DRPs was problems related to drug selection. Based on the chi-square analysis, there was no relationship between potential DRPs of antibiotic use and the therapeutic outcome. In addition, there was also no relationship between potential DRPs of antibiotic use and patient’s length of stay. Conclusions The potential DRPs of antibiotics use do not have a significant effect on the therapeutic outcome and length of stay of the gastroenteritis patients in Universitas Gadjah Mada Hospital.

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KAJIAN DRUG RELATED PROBLEMs PENGGUNAAN ANTIBIOTIK PADA PASIEN PEDIATRIK DI RSUD KOTA SEMARANG

Cited by 2 publications

References 4 publications

Drug-related problems (DRPs) on antibiotic therapy in pediatric patients: a review

Drug-related problems (DRPs) on antibiotic therapy in pediatric patients: a review

Drug-related problems of antibiotic use in gastroenteritis related to patient therapy outcomes at Universitas Gadjah Mada Hospital

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