“…In 1966, the low frequency antigen, Kamhuber, was reported [3] as being re sponsible for a severe transfusion reaction in a multi-transfused haemophilic patient, F. S. The antibody was active by the anti globulin technique reacting with a pure antiIgG, and by the conglutination test. The antigen was considered to be inherited but was detected only on the donor's brother's red cells; none of the other family members and 1,100 Viennese donor samples reacted.…”