Kaposi Sarcoma and Polymyositis

Dantzig, Paul I.

doi:10.1001/archderm.1974.01630100061016

Cited by 33 publications

(8 citation statements)

References 11 publications

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“…Other patients receiving immunosuppressive drugs, including a patient with systematic lupus erythematosus (Klein et al, 1974) and a patient with myasthenia gravis (Ulbright and Santa Cruz, 1981), have developed Kaposi's sarcoma. It has also been described in a number of other disorders of the immune system, including immunodeficiencies, paraproteinemias, polymositis, and pemphigus (Dantzig, 1974;Law, 1974;Safai, 1984;Ulbright and Santa Cruz, 1981). Second malignancies are very commonly associated with Kaposi's sarcoma, occurring in 19 to 37% of cases of classical Kaposi's sarcoma (DiGiovanna and Safai, 1981;Reynolds et al, 1965;Safai et al, 1980).…”

Section: Etiologic Considerationsmentioning

confidence: 99%

Malignancies in the acquired immunodeficiency syndrome

1988

J. Elec. Microsc. Tech.

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Malignancies frequently arise in patients infected with human immunodeficiency virus (HIV), including those patients classified as having the acquired immunodeficiency syndrome (AIDS). Currently, Kaposi's sarcoma and certain types of lymphoma are considered to develop as a result of HIV infection, and other cancers have also been reported in these patients. For the most part, ultrastructural study of HIV-associated malignancies has been limited to Kaposi's sarcoma; the ultrastructural features of the epidemic form of this disease are generally the same as those of the classical form. The occurrence of these cancers in HIV-infected individuals appears to be related to the immunodeficiency caused by this virus, but the basic etiologic mechanisms remain unknown. In general, only palliative treatments are presently available for HIV-associated malignancies.

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Section: Etiologic Considerationsmentioning

confidence: 99%

Malignancies in the acquired immunodeficiency syndrome

1988

J. Elec. Microsc. Tech.

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“…KS has also been seen following immunosuppressive therapy for aplastic anemia, 15 idiopathic thrombocytopenic purpura, 27 hemolytic anemia, 28 asthma, 14,19 nephrotic syndrome, 19 polymyalgia rheumatica, 19 polymyositis, 29 dermatomyositis, 30 rheumatoid arthritis, 9,19 systemic lupus erythematosus, 31 and temporal arteritis 32 . KS has also occurred following immunosuppressive therapy (prednisone and/or azathioprine) for another immunobullous disease other than pemphigus, bullous pemphigoid 19,33,34 …”

Section: Discussionmentioning

confidence: 99%

Pemphigus and Kaposi's Sarcoma

Kaplan¹,

Israel²,

Ahmed³

1989

The Journal of Dermatologic Surgery and Oncology

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A 77-year-old woman developed Kaposi's sarcoma (KS) during prednisone therapy for pemphigus foliaceus. There are 7 prior reports in the literature of KS occurring in association with pemphigus. There are multiple reports of KS occurring in patients without pemphigus who are immunosuppressed either by malignancy or by chemotherapy for various disorders. Although the relationship between KS and pemphigus is a real one, KS is more likely related to therapeutically induced immunosuppression in certain predisposed individuals rather than primarily to pemphigus itself.

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“…An increased incidence of KS has been reported in association, with a variety of immunologic disorders such as immune deficiency, plasma cell dyscrasia, thymoma, and polymyositis. [7][8][9] There are two suggested mechanisms by which the immune system could contribute to the development of Kaposi's sarcoma, immunosuppression and immune stimulation.…”

Section: Discussionmentioning

confidence: 99%

“…1,8 Herpes virus-like particles have been seen with the electron microscope in cell cultures from patients with KS. 10 In addition, a serologic association has been demonstrated between the cytomegalic virus (CMV) and KS from African, European, as well as North American patients.…”

Section: Discussionmentioning

confidence: 99%

Kaposi's Sarcoma in Recipients of Renal Transplants

Akhtar¹,

Bunuan²,

Ali³

et al. 1982

Ann Saudi Med

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Two cases of Kaposi's (KS) sarcoma developing in renal transplant recipients are presented. One patient, in whom the disease was limited to skin and oropharynx, responded dramatically to reduction of immunosuppressive therapy and is alive and well 22 months following diagnosis. The second patient, who had more widespread skin involvement, died three months after diagnosis. World literature pertaining to KS in renal transplant is reviewed and current thinking with regard to pathogenesis and management of KS in these patients is discussed.

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Kaposi Sarcoma and Polymyositis

Cited by 33 publications

References 11 publications

Malignancies in the acquired immunodeficiency syndrome

Malignancies in the acquired immunodeficiency syndrome

Pemphigus and Kaposi's Sarcoma

Kaposi's Sarcoma in Recipients of Renal Transplants

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