Kaposi varicelliform eruption induced by methotrexate in an adult atopic dermatitis patient

Background: “Kaposi varicelliform eruption” (KVE), also known as “eczema herpeticum,” refers to a rare widespread skin infection. The primary causal agent is thought to be the herpes simplex virus (HSV). Though common in patients with underlying skin dermatosis, systemic immunosuppression can at times lead to KVE.Case Presentation: A 27‐years male, a renal transplant recipient, under systemic immunosuppressants, presented with lesions over the whole body for 2 weeks and fever for 10 days. Skin examination revealed multiple flaccid vesicles with hemorrhagic fluid over the face, trunk, and bilateral extremities. Multiple erythematous erosions over the chest and abdomen, multiple petechiae and purpura over bilateral legs, palms, soles, and abdomen, erosions over the hard palate along with thick crusts over the scalp. A tzanck smear showed plenty of acantholytic cells. With a diagnosis of KVE, he was managed with an injection of acyclovir that led to resolution of his symptoms.Conclusion: KVE is a serious condition that may have fatal outcomes. Early diagnosis and appropriate treatment of patients at risk for viral complications are very important medical considerations.

show abstract

Kaposi varicelliform eruption induced by methotrexate in an adult atopic dermatitis patient

Cited by 4 publications

References 8 publications

Kaposi varicelliform eruption

Kaposi varicelliform eruption

Methotrexate

Kaposi Varicelliform Eruption in a Chronic Kidney Disease Individual Under Tacrolimus: A Case Report

Contact Info

Product

Resources

About