Kaposiform hemangioendothelioma in an adult with an unusual presentation

Abstract

detectable by PCR in PBMC. If such is indicative of active infection, 30% of healthy individuals would be having active HHV-7 infection at any one time point.In summary, we compliment Vág et al. in having reported a high-quality study with a novel approach, but are unconvinced that their results provide conclusive evidence of recent primary HHV-7 infection in young adults with PR. References1 Vág T, Sonkoly E, Kárpáti S, Kemény B, Ongrádi J. Avidity of antibodies to human herpesvirus 7 suggests primary infection in young adults with pityriasis rosea. J Eur Acad Dermatol Venereol 2004; 18: 738 -740. 2 Kosuge H, Tanaka-Taya K, Miyoshi H et al. Epidemiological study of human herpesvirus-6 and human herpesvirus-7 in pityriasis rosea. Br J Dermatol 2000; 143: 795-798. 3 Yasukawa M, Sada E, Machino H, Fugita S. Reactivation of human herpesvirus 6 in pityriasis rosea. Br J Dermatol 1999; 140: 169 -170. 4 Chuh AAT, Chiu SSS, Peiris JSM. Human herpesvirus 6 and 7 DNA in peripheral blood leukocytes and plasma in patients with pityriasis rosea by polymerase chain reaction -a prospective case control study. Acta Derm Venereol 2001; 81: 289-290. 5 Chan PK, Peiris JS, Yuen KY et al. Human herpesvirus-6 and human herpesvirus-7 infections in bone marrow transplant recipients. J Med Virol 1997; 53: 295 -305. 6 Vág T, Sonkoly E, Kemeny B et al. [Studies on the novel association of human herpesvirus-7 with skin diseases.].

Violaceous annular plaques on the abdomen in a middle‐aged woman

“…It can be differentiated from tufted angioma by deeper and infiltrative growth pattern. Although common in childhood, KMP has not been reported in adults 4 …”

“…Based on the clinicopathological findings, other differential diagnoses that need to be ruled out include kaposiform hemangioendothelioma, kaposi sarcoma and eccrine angiomatous hamartoma. Kaposiform hemangioendothelioma is a locally aggressive vascular tumor that typically occurs in infants and children and is rarely encountered in adults 4,5 . It manifests as ill‐defined violaceous ulcerated plaques on the extremities and trunk.…”

Adult Kaposiform Hemangioendothelioma of the Leg Complicated by Kasabakh Meritt Phenomenon.

“…Fernandes and all, reviewed all the articles talking about HEK and KMP and published in Pub Med, from April 1993 to July 2007, he found that only 20 adults were recorded (2,6,7,8,9,10,11,12,13) Since then, some other cases, about twelve, have been described all over the world. (14,15,16,17,18,19,20,21,22) The KHE has got two clinical presentations : cutaneous and visceral.…”

CyberKnife Treatment for Kaposiform Hemangioendothelioma of the Ilium in an Adult: Case Report and Review of the Literature

“…Common tumor locations included the extremities (9 cases, 39.1%), the torso (7 cases, 30.4%), and the cervicofacial region (5 cases, 21.7%). In adults, KHE usually involves dermal and subcutaneous tissues (65.2%) [1,2,3,4,5,6,7,8,9,11,13,14,17]. None of the 23 cases showed evidence of KMS, and just 2 patients had lymphangiomatosis (8.7%) [1,11].…”

“…KHE typically occurs during infancy and in the first decade of life. Although KHE may also develop in adults, only approximately 20 adult KHE patients have been reported (table 1) [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17]; most of them were not associated with KMS [6]. KHE rarely originates from bone without accompanying cutaneous changes.…”