Kartagener Syndrome: A Case Report

Najafi, Samane; Mohammadpour, Ali; Eshghizadeh, Maryam

doi:10.22159/ajpcr.2018.v11i5.25593

Cited by 7 publications

(5 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Given its genetic nature, Kartagener's syndrome lacks a specific curative treatment. Management of affected individuals focuses on addressing symptoms, often involving the periodic or continuous use of antibiotics through oral or intravenous routes to manage respiratory infections [ 9 ]. Our patient, according to his mother, did indeed receive many courses of antibiotic therapy that did not stop infections from persisting and/or recurring and eventually the patient developed massive hemoptysis.…”

Section: Discussionmentioning

confidence: 99%

A rare case report: Left middle lobectomy in recurrent hemoptysis and chest infections of Kartagener syndrome patient

Fatimi,

Wahab,

Mir

et al. 2024

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

A rare case report: Left middle lobectomy in recurrent hemoptysis and chest infections of Kartagener syndrome patient

Fatimi,

Wahab,

Mir

et al. 2024

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

“…Early diagnosis of KS is crucial to prevent progressive worsening of lung function. 14 The Pneumococcal and influenza vaccination should be given to prevent frequent infections. 18 Functional endoscopic sinus surgery (FESS) can be considered to relieve chronic rhinosinusitis.…”

Section: Discussionmentioning

confidence: 99%

Kartagener Syndrome: A Case Report

Willim

Pebriadi

Munthe³

et al. 2022

AMCR

View full text Add to dashboard Cite

Kartagener syndrome (KS) is a rare autosomal recessive disorder characterized by a clinical triad of situs inversus, chronic sinusitis, and bronchiectasis. Impaired ciliary motility due to abnormal ciliary structure or function is the main pathophysiological problem in KS. A 38-year-old woman presented to our outpatient clinic with a productive cough, fever, and shortness of breath for 1 month. She has had recurrent episodes of respiratory tract infections since childhood. Clinical investigations revealed situs inversus, sinusitis, and bronchiectasis. She was diagnosed with KS and treated with antibiotics, mucolytics, bronchodilators, and chest physiotherapy. Patients with KS present with chronic recurrent respiratory tract infections due to ineffective mucociliary clearance. Early diagnosis is important to improve prognosis. The main goals in the management of KS are to prevent the progression of the disease, preserve pulmonary function, and improve quality of life.

show abstract

“…PCD is a genetic disease and has no definitive treatment. Treatments for these patients are mainly symptomatic treatments that include intermittent or constant oral or intravenous administration of antibiotics to treat respiratory infections, inhaled bronchodilators, mucolytics, oral corticosteroids, and chest physiotherapy for bronchiectasis and pneumonia [ 27 ]. Administration of the annual influenza vaccine and regular doses of the pneumococcus vaccine as a part of the childhood immunization program is also necessary to prevent frequent infections [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

A Novel DNAH9 Gene Mutation Causing Primary Ciliary Dyskinesia With an Unusual Association of Jejunal Atresia in a Bahraini Child

Isa¹,

Alkharsi²,

Busehail³

et al. 2022

Cureus

View full text Add to dashboard Cite

Primary ciliary dyskinesia (PCD) is a rare autosomal recessive genetic disorder. It is caused by a defect in the action of the cilia lining multiple organs of the body, including the lungs, the sinuses, hepatobiliary and reproductive organs. In general, the estimated prevalence of this condition is one in 15,000-20,000 individuals. It is characterized by the triad of chronic sinusitis, bronchiectasis, and situs inversus, which occurs in 50% of the cases. It can be associated with other diseases too. Genetic studies can aid in confirming the diagnosis of this condition. A high degree of suspicion about PCD among pediatricians, neonatologists, otorhinolaryngologists, and pulmonologists is essential to make early referrals of patients before they develop irreversible lung damage. Hence, early diagnosis and appropriate treatment are very important. Multicenter collaborations might improve the quality of treatment and patient outcomes. Here, we discuss a case of PCD with a unique association with type IIIb jejunal atresia, and developmental delay secondary to vitamin B12 deficiency. Moreover, the patient was found to have a novel DNAH9 gene mutation in a compound heterozygous state. This is the first case of this rare disease to be reported from Bahrain. This case report is also associated with an extensive literature review.

show abstract

Kartagener Syndrome: A Case Report

Cited by 7 publications

References 11 publications

A rare case report: Left middle lobectomy in recurrent hemoptysis and chest infections of Kartagener syndrome patient

A rare case report: Left middle lobectomy in recurrent hemoptysis and chest infections of Kartagener syndrome patient

Kartagener Syndrome: A Case Report

A Novel DNAH9 Gene Mutation Causing Primary Ciliary Dyskinesia With an Unusual Association of Jejunal Atresia in a Bahraini Child

Contact Info

Product

Resources

About