Keratin degradation by fungi isolated from the grounds of a gelatin factory in Jabalpur, India

Almost 300 common fungi were screened for synthesis of extracellular keratinases. About 54% of the fungi grew on agar plates with soluble keratin and excreted the enzymes. Some representatives of Fusarium, Acremonium and Geotrichum were the most active. However, when cultivating the promising strains in submerged conditions in a medium with porcine nail as the sole source of carbon and nitrogen, other fungi proved to be potent. Aspergillus flavus was the most powerful producer of extracellular keratinases, followed by Alternaria radicina, Trichurus spiralis and Stachybotrys atra.

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“…Geotrichum candidum degraded chicken feathers ( Singh et al . 1995 ) and human hair ( Rayak et al . 1991 ).…”

Section: Resultsmentioning

confidence: 99%

Screening fungi for synthesis of keratinolytic enzymes

Friedrich

Gradišar

Mandin

et al. 1999

Letters in Applied Microbiology

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“…The successful culture in pure growth, of Geotrichum candidum from different skin specimens collected at two different time points confirmed the etiology of this skin disease. The lack of fungus seen on histology is attributed to the lack of crusts submitted for examination, as this fungus is known to be keratinophilic [27] and possibly also to the limited number of biopsy samples taken from not ideal sites. The histopathology changes were disappointing as changes were non-specific in character, but consistent with chronic antigenic stimulation of the epidermis with epidermal hyperplasia and inflammation confined to the superficial dermis.…”

Section: Discussionmentioning

confidence: 99%

Rare Generalized Form of Fungal Dermatitis in a Horse: Case Report

Padalino

Sandy

Barrasso

et al. 2020

Animals

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A rare case of Geotrichum spp. dermatitis in a horse is presented. After unrelated, previous surgery and antibiotic treatment, a saddle horse showed well-circumscribed areas of non-pruritic alopecia. Suspecting allergic skin disease, the horse was treated with corticosteroids. The skin lesion spread, and a second veterinarian was consulted. At clinical examination, the horse was lethargic, pyretic and hair was shedding/easily epilated over the head, neck, shoulders, and legs and the hind legs were swollen. Blood analysis revealed mild leucocytosis and hyperglobulinemia. Hair, skin scraping, and skin biopsy ruled out parasites and bacteria; cytology identified yeast-like structures with hyphae or pseudohyphae. Geotrichum candidum was isolated on culture. Treatment consisted of stable disinfection, topical application of an antifungal solution, vitamins C and E supplementation and allowing the horse to graze in sunlight for at least 6 h/day. At 3-weeks follow-up, the horse had gained weight, alopecia was decreased, and all other clinical parameters were normal. Antifungal treatment was continued twice a week for three months. This study suggests Geotrichum candidum may cause skin lesions in horses after long-term use of corticosteroids or antibiotics. To avoid unnecessary and prolonged suffering in cases of dermatitis, veterinarians should be promptly consulted, appropriate diagnostic procedures conducted, so that a definitive diagnosis can be reached, and an appropriate treatment regimen implemented.

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“…Talaromyces flavus isolated from paddy rhizosphere of Darjeeling Hills exhibited phosphate solubilizing activity in vitro and positively influenced the growth of Oryza sativa, Cicer arietinum, and Vigna radiata under greenhouse conditions (Chakraborty et al 2011). A keratin degrading strain of T. trachyspermus was isolated from the grounds of a gelatin factory in Jabalpur, Madhya Pradesh, and digested human hair in stationary culture (Rajak et al 1991). Talaromyces trachyspermus was reported as a soil saprophyte in paddy fields of Orissa (Dutta and Ghosh 1965).…”

Section: Discussionmentioning

confidence: 99%

Morphology and multigene phylogeny of Talaromyces amyrossmaniae, a new synnematous species belonging to the section Trachyspermi from India

Rajeshkumar¹,

Yılmaz²,

Marathe³

et al. 2019

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A newTalaromycesspecies,T.amyrossmaniae, isolated from decaying fruit and litter ofTerminalia bellerica, is described and illustrated. On the natural substrate, the new species produces determinate synnemata, with a well-defined, vivid orange red to orange red cylindrical stipe, and a greyish green capitulum. Conidiophores are typically biverticillate, or sometimes have subterminal branches, with acerose phialides that produce globose to subglobose, smooth to slightly roughened conidia. Multigene phylogenetic analyses based on the internal transcribed spacer region (ITS), and partial sequences of β-tubulin (BenA), calmodulin (CaM), and DNA directed RNA polymerase second large subunit (RPB2) genes, along with morphological characterization, revealed that these isolates are distinct and form a unique lineage of Talaromyces in section Trachyspermi, closely allied toT.aerius,T.albobiverticillius,T.heiheensis,T.erythromellis, andT.solicola. The new speciesT.amyrossmaniaeis the first species in section Trachyspermi with determinate synnemata.

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Keratin degradation by fungi isolated from the grounds of a gelatin factory in Jabalpur, India

Cited by 31 publications

References 11 publications

Screening fungi for synthesis of keratinolytic enzymes

Screening fungi for synthesis of keratinolytic enzymes

Rare Generalized Form of Fungal Dermatitis in a Horse: Case Report

Morphology and multigene phylogeny of Talaromyces amyrossmaniae, a new synnematous species belonging to the section Trachyspermi from India

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