“…In our series IHC was used to assess ALN of all lobular tumors when routine H&E was negative. While contribution of IHC over H&E to improve lymph nodal staging in ILC remains controversial [18,19], one could assume the possibility of a higher false negative rate in the non-ILC group since IHC was not performed in these cases. Therefore, we might even be underestimating differences in ALN involvement between ILC and non-ILC.…”