Keratoplasty in the United States

An 11-Year Review of Keratoplasty in a Tertiary Referral Center in Turkey: Changing Surgical Techniques for Similar Indications

“…1,2,8,12,13,16 However, one recent study conducted in the US concluded that DSAEK is the most preferred technique and surpassed PK from 2011 on. 11 In fact, predominance of lamellar techniques in the last years of the study periods was reported in several studies including present one. 1,2,7,10,12,16 Thus, current data indicate that PK will decrease in prevalence relative to lamellar techniques in the future.…”

“…[8][9][10] In the last decade, improved (partial thickness) lamellar keratoplasty (LK) techniques that focused on replacing the diseased layers of the cornea were introduced and implemented widely in developed countries. 1,11 Major advantages of anterior LK over PK are elimination of endothelial allograft rejection with a concomitant reduction in overall graft rejection rates and lower long-term endothelial cell loss of host endothelium. Posterior LK techniques afford much faster visual rehabilitation with less postoperative astigmatism and better anatomical results when compared with PK.…”

“…Accordingly, a major shift has begun away from PK and toward LK in developing countries as well. 1,7,11,12 With these improved outcomes associated with LK techniques, we believe it is necessary for tertiary referral centers in the developing world to stay up to date and use increase utilization of these state-of-the art treatment modalities. Therefore, we initiated this study to determine the trends of clinical indications and corneal transplantation techniques in "2004 to 2014" period, which includes implementation of anterior and posterior LK techniques to our clinics.…”

Comparative assessment of the efficacy of primary and secondary corneal endothelial dystrophy treatment by isolated descemetorhexis and accelerated collagen crosslinking method

“…Это связано с проблемой организации банков органов и тка-ней, а также с отсутствием во многих лечебных учреждениях РФ официальных разрешений для работы с трупными роговицами. Как правило, показанием к пересадке роговицы служит эндо-телиальная дистрофия [14], поэтому разработка новых не трансплантационных методов лечения эндотелиальной дистрофии роговицы (ЭДР) оста-ётся весьма актуальной.…”

In Vitro Study of the Deturgescence Ability of Cultivated Human Corneal Endothelial Cells

“…1,2 Penetrating keratoplasty (PKP) was the gold standard for treating these conditions until recently, when lamellar techniques such as Descemet stripping endothelial keratoplasty and Descemet membrane (DM) endothelial keratoplasty were introduced and adopted by a large number of corneal surgeons. 3,4 In both PKP and lamellar techniques, there is an obvious need for human donors and corneal grafts, which may not always be available. With the considerable increase in the number of people in need of this operation, researchers have been trying to develop alternative approaches, such as the use of bioengineered structures to cope with the ongoing increasing demands.…”