Ketoprofen‐induced photoallergic consort contact dermatitis: A difficult diagnosis

Herzum, Astrid; Cozzani, Emanuele; Parodi, Aurora; Gallo, Rosella

doi:10.1111/cod.14058

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…In photoallergic or phototoxic contact dermatitis from topical drugs, lesions occur in the area of concomitant drug application and sun exposure, but distant lesions can occur in areas of accidental contact, as a in a contra-lateral limb (kissing faces of the legs) or in areas of inadvertent spread by the hands or contaminated objects 28,29 . Cases of connubial dermatitis have been described, mainly for ketoprofen and benzydam ine 26,[30][31][32] . When used as a mouthwash these non-steroidal anti-inflammatory drugs (NSAIDs) induce mostly lip and chin dermatitis 26,33 .…”

Section: Acute Photosensitivitymentioning

confidence: 99%

Drug-induced photosensitivity

Gouveia

Gameiro

Coutinho

et al. 2023

PJDV

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Drug photosensitivity is a relatively frequent adverse event, although not always recognized due to its clinical polymorphism and difficulties in performing tests to prove drug causality.The aim of this report is to review the mechanisms of photosensitivity related with topical and systemic drugs (phototoxicity, photoallergy, autoimmunity, and enhanced photocarcinogenesis), the main acute and delayed clinical manifestations (acute sunburn or eczema, pseudoporphyria, photo-onycholysis, dyschromia, telangiectasia, subacute lupus erythematosus, pre-cancerous lesions, and cutaneous neoplasia), the main culprits [non-steroidal anti-inflammatory drugs (NSAIDs), antimicrobials, like fluoroquinolones and tetracyclines, psychotropic, anticancer, and cardiovascular drugs] and the most adequate diagnostic procedures (photopatch and drug photoprovocation tests).

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