Thanks to the Covid-19 epidemic, the last two years have been full of changes for entrepreneurs. Managing and measuring business performance is important for businesses because it allows them to identify the potential of the business and determine its strength in the market environment, as demonstrated by the current situation in the Covid-19 pandemic. The purpose of this article is to present the results of the response of entrepreneurs to the situation in Covid-19 based on primary research in 295 companies in the Czech Republic in relationship to strategic goals and business environment evaluation. The results showed that these entrepreneurs wanted to change their main objectives to long term sustainability at first. More than 50.5% of respondents do not plan to close their business activities in the near future.