Kidney Mass and Relative Medullary Thickness of Rodents in Relation to Habitat, Body Size, and Phylogeny

Alkahtani, Mohammed Ali; Zuleta, Carlos; Caviedes‐Vidal, Enrique; Garland, Theodore

doi:10.1086/420941

Cited by 75 publications

(78 citation statements)

References 83 publications

(53 reference statements)

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“…Clearly, some of the interspecific variation in body size would remain if all animals had been raised on the same food, etc. (see also Ashton et al 2000;Al-kahtani et al 2004), but whether that is true for mass-corrected BMR or MMR is unknown, and complicated effects of genotype-environment interaction are possible. In our opinion, a major goal of future comparative studies (at least for experimentally tractable groups, e.g., see Mueller and Diamond 2001) should be to obtain data from animals born and raised under common conditions, although this obviously does not apply in any simple way for ''traits'' that are inherently measured in nature, such as home range, latitude, and environmental temperatures Garland et al 1992;Blomberg et al 2003).…”

Section: Phylogenetic Signal In Ecological and Physiological Traitsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Climatic Adaptation and the Evolution of Basal and Maximum Rates of Metabolism in Rodents

Rezende¹,

Bozinovic²,

Garland³

2004

Evol

103

199

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Abstract. Metabolic rate is a key aspect of organismal biology and the identification of selective factors that have led to species differences is a major goal of evolutionary physiology. We tested whether environmental characteristics and/or diet were significant predictors of interspecific variation in rodent metabolic rates. Mass-specific basal metabolic rates (BMR) and maximum metabolic rates (MMR, measured during cold exposure in a He-O 2 atmosphere) were compiled from the literature. Maximum (Tmax) and minimum (Tmin) annual mean temperatures, latitude, altitude, and precipitation were obtained from field stations close to the capture sites reported for each population (N ϭ 57). Diet and all continuous-valued traits showed statistically significant phylogenetic signal, with the exception of masscorrected MMR and altitude. Therefore, results of phylogenetic analyses are emphasized. Body mass was not correlated with absolute latitude, but was positively correlated with precipitation in analyses with phylogenetically independent contrasts. Conventional multiple regressions that included body mass indicated that Tmax (best), Tmin, latitude, and diet were significant additional predictors of BMR. However, phylogenetic analyses indicated that latitude was the only significant predictor of mass-adjusted BMR (positive partial regression coefficient, one-tailed P ϭ 0.0465). Conventional analyses indicated that Tmax, Tmin (best), and altitude explained significant amounts of the variation in mass-adjusted MMR. With body mass and Tmin in the model, no additional variables were significant predictors. Phylogenetic contrasts yielded similar results. Both conventional and phylogenetic analyses indicated a highly significant positive correlation between residual BMR and MMR (as has also been reported for birds), which is consistent with a key assumption of the aerobic capacity model for the evolution of vertebrate energetics (assuming that MMR and exercise-induced maximal oxygen consumption are positively functionally related). Our results support the hypothesis that variation in environmental factors leads to variation in the selective regime for metabolic rates of rodents. However, the causes of a positive association between BMR and latitude remain obscure. Moreover, an important area for future research will be experiments in all taxa are raised under common conditions to allow definitive tests of climatic adaptation in endotherm metabolic rates and to elucidate the extent of adaptive phenotypic plasticity.Key words. Bergmann's rule, body size, comparative method, diet, endothermy, energetics, temperature.Received August 29, 2003. Accepted February 8, 2004 Identification of the selective factors that have led to interspecific diversification in metabolic rates has been a major goal of ecological and evolutionary physiology (Garland and Carter 1994;Spicer and Gaston 1999;Walters and Reich 2000;McNab 2002). The most common approach is to correlate species or population differences in metabolic rate with variation in var...

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Section: Phylogenetic Signal In Ecological and Physiological Traitsmentioning

confidence: 99%

mentioning

confidence: 99%

Climatic Adaptation and the Evolution of Basal and Maximum Rates of Metabolism in Rodents

Rezende¹,

Bozinovic²,

Garland³

2004

Evol

103

199

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“…As expected, P. darwini renal functioning was affected by water availability and temperature. Rodents reared in warm conditions had higher RMT and UCA values, indicating that renal structure and function are coupled (Al-Kahtani et al, 2004). When P. darwini individuals experienced an increase in water availability or a decrease in ambient temperature, they exhibited short-term acclimation in terms of their osmoregulatory traits.…”

Section: Discussionmentioning

confidence: 98%

“…For endotherms, increased ambient temperatures along with decreased availability of drinking water favor physiological adjustments that promote water and energy storage (Al-Kahtani et al, 2004;Bozinovic and Gallardo, 2006;Bozinovic et al, 2003;Hinsley et al, 1993;Hudson and Kimzey, 1966;Krebs, 1950). Initial thermal conditions may also influence an organism's acclimation capability (Barceló et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Early life experience drives short-term acclimation of metabolic and osmoregulatory traits in the leaf-eared mouse

Cavieres

Nuñez-Villegas

Bozinovic

et al. 2017

Journal of Experimental Biology

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We studied the putative effect of early life experience on the physiological flexibility of metabolic and osmoregulatory traits in the leaf-eared mouse, Phyllotis darwini, an altricial rodent inhabiting seasonal Mediterranean environments. Adult individuals were collected in central Chile and maintained in breeding pairs. Pups were isolated after weaning and acclimated to different temperatures (cold or warm) and water availability (unrestricted and restricted) until adulthood. Subsequently, individuals were re-acclimated to the opposite treatment. Rodents reared in the warm and subjected to water restriction had lower basal metabolic rate (BMR), total evaporative water loss (TEWL) and body mass (M b ) compared with those developing in the cold treatment; nevertheless, individuals subjected to warm temperatures had greater relative medullary thickness (RMT) and urine concentrating ability (UCA). Cold-reared rodents re-acclimated to warm conditions exhibited physiological flexibility of metabolic traits; however, their osmoregulatory attributes did not vary. Conversely, warm-reared rodents re-acclimated to cold had reduced RMT and UCA, but the metabolic traits of these individuals did not change. These results suggest a trade-off between metabolic performance and renal capabilities that might hinder physiological acclimation. Our results support the hypothesis of ontogenetic dependence of short-term acclimation in osmoregulatory and metabolic traits in P. darwini.

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“…The kidneys receive blood from the renal arteries, right and left, which branch directly from the abdominal aorta. Despite their relatively small size, the kidneys receive approximately 20% of the cardiac output (Al-kahtani et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Dietary conjugated linoleic acid isomers and selenite or selenized yeast affect fatty acid concentration in the kidneys of rats

Czauderna¹,

Kowalczyk²,

Krajewska³

et al. 2011

J. Anim. Feed Sci.

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The influence of diets enriched in a mixture of conjugated linoleic acid (CLA) isomers (CLAmix) and/or selenium as Na 2 SeO 3 (SeIV) or selenized yeast (SeY) on feed intake, kidneys' weight and the concentrations of fatty acids (FA) in the kidneys of rats was investigated. The study was performed on 80 female Wistar rats (Hsd Brl Han: WIST), 8 weeks of age with an initial body weight of 195.7±0.8 g. Each group numbered 8 rats. During the 7-day preliminary period the rats were fed a standard Labofeed H diet at a sub-maintenance level. Next, for 6 weeks the rats were fed ad libitum on the experimental diets supplemented with CLAmix, 0.2 ppm Se or 0.5 ppm Se as SeIV ( L SeIV or H SeIV, respectively) and SeY ( L SeY or H SeY, respectively). The rats were sacrificed at the end of the six-week experimental period. The diets enriched in CLAmix or Se (as SeIV or SeY) showed a negligible effect on kidneys' weight, although the diets containing simultaneously CLAmix and Se numerically increased kidneys' weight compared with the control animals. The addition of CLAmix to the diet, regardless of the higher level of SeY, showed a tendency to decrease in feed intake and decreased the concentrations of saturated (SFA), mono-(MUFA) and polyunsaturated (PUFA) fatty acids in comparison with the control rats. Dietary SeIV or SeY, irrespective of the concentration of extra Se, decreased the concentration of unsaturated fatty acids (UFA) and the sum of all assayed fatty acids (ΣFA) in the kidneys. The diet containing CLAmix and Se as H SeIV or L SeY decreased the concentrations of SFA, MUFA and PUFA in the kidneys compared with the control rats. On the other hand, the addition of L SeIV or, especially, H SeY to the diet enriched in CLAmix resulted in an increasing in the concentrations of SFA, MUFA and PUFA in the kidneys compared with the control group and rats fed the diets containing CLAmix, SeIV or SeY. The diet enriched in CLAmix and HSeY most effectively stimulated the accumulation of CLA isomers with the exception of cis11trans13CLA in the kidneys in comparison with other diets. Dietary CLAmix decreased the

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Kidney Mass and Relative Medullary Thickness of Rodents in Relation to Habitat, Body Size, and Phylogeny

Cited by 75 publications

References 83 publications

Climatic Adaptation and the Evolution of Basal and Maximum Rates of Metabolism in Rodents

Climatic Adaptation and the Evolution of Basal and Maximum Rates of Metabolism in Rodents

Early life experience drives short-term acclimation of metabolic and osmoregulatory traits in the leaf-eared mouse

Dietary conjugated linoleic acid isomers and selenite or selenized yeast affect fatty acid concentration in the kidneys of rats

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