Kidney Stones Formation and Use of Medicinal Plants as Antiurolithiatic Agents

Abstract

There is an old and famous fact "the garden is the poor man's apothecary" and treatment of each and every disease is hidden in nature. Medicinal plants are highly esteemed all over the world as a rich source of therapeutic agents for the prevention and treatment of various diseases. Since ages, herbs are being used for treating different ailments in different parts of world by different communities. A kidney stone, also known as a renal calculus is a solid concretion or crystal aggregation formed in the kidneys from dietary minerals in the urine. The problem of urinary stones or calculi is a very ancient one these stones are found in all parts of the urinary tract, the kidney, and the urinary bladder and may vary considerably in size. Urolithiasis is a complex process that occurs from series of several physicochemical event including super-saturation, nucleation, growth, aggregation and retention within the kidneys. Present article deals with reason, types of kidney stones, risk factors associated, diagnosis and treatment methods including many medicinal plants as herbal option for treatment of urinary stones.

Antiurolithiatic effects of pentacyclic triterpenes: The distance traveled from therapeutic aspects

“…The key factor that triggers the formation of stones is the supersaturation of urine, or when urine lacks the normal inhibitors (for example citrate, magnesium, and glycosaminoglycans [GAGs]) of stone formation. This process of stone formation is influenced by several environmental and nutritional factors, such as low urinary volume, diets rich in animal protein, vitamin abnormalities such as vitamin A deficiency or excess vitamin D, as well as metabolic alterations (for example hypercalciuria, hyperuricosuria, and cystinuria) (Arya, Pandey, & Verma, 2017;Kasote, Jagtap, Thapa, Khyade, & Russell, 2017).…”

Clinical Potential of Himalayan Herb Bergenia ligulata: An Evidence-Based Study

“…It is estimated that 80% of people worldwide depend on such plant-based traditional medicines for their treatment, and their usage is predominant in developing countries [ 2 ]. In recent years, natural products have received renewed global attention from the clinical point of view due to low toxicity, low side effects, cost-effectiveness, and easy accessibility, as compared to modern synthetic medicines [ 3 , 4 ]. Bergenia ligulata is a perennial Himalayan herb belonging to the family Saxifragaceae.…”

Curative Effects of Ethanol Extract of Prosopis Farcta (Syrian Mesquite) Against Ethylene Glycol Induced Urolithiasis in Male Albino Rats

“…They cause sever hemorrhage, strong ache, close the flow of urine through urinary tract and other risks, due to they necessary to take or break by operation (Bahmani et al, 2016). Recently, it has been investigated that renal calculi affecting nearly 12% of the population, with a rate of recurrence 47-60% in female, and 70-81% in males (Arya et al, 2017). It has been investigated that calcium oxalate (CaOx) urolithiasis model which induced by administration of EG (precursor of oxalate formation) use to study the effect of kidney stone on experimental model in rats (Mahmud et al, 2021).…”