Kikuchi–Fujimoto Disease: A Study of 24 Cases

Supari, Divya; Ananthamurthy, Anuradha

doi:10.1007/s12070-013-0672-4

Cited by 11 publications

(17 citation statements)

References 13 publications

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“…In a recent study from Japan, there were however, more females than male diagnosed with this disease; and the age was reported to vary from 5 to 80 years, although most of the patients (62.7%) were younger than 30 years (Asano et al, 2014). Similar was the observation of Indian worker, although in a smaller series; who report that of their 24 cases, 17 were females and 7 were males (Supari and Ananthamurthy, 2014). From KSA, out of a total of 2500 lymph node biopsies, 15 cases were diagnosed as Kikuchi disease.…”

Section: Discussionmentioning

confidence: 66%

Pattern of Lymph Node Pathology in Western Saudi Arabia

Albasri

El-Siddig²,

Hussainy³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: This study aimed to characterize the histopathological pattern of lymph node pathology among Saudi patients and to highlight the age and gender variations of these lesions as base line data. Materials and Methods: We retrospectively analyzed the data from lymph node biopsy specimens received at the Department of Pathology, King Fahad Hospital, Madinah, Saudi Arabia from January 2006 to December 2013. Results: Of the 289 lymph node biopsy specimens received, 154 (53.3%) were from males and 135 (46.7%) from females giving a male: female ratio of 1.14:1. Age of the patients ranged from 2.5 to 96 years with a mean age 33.9 years. The commonest lymph node group affected was the cervical (30.4%) followed by axillary (9.7%) and inguinal (8.7%). Malignant lymphoma [71 Hodgkin's disease (HD), 57 non Hodgkin's lymphoma (NHL)] 128 (44.3%), reactive hyperplasia 68 (23.5%), and tuberculosis 41 (14.2%) were the common causes of lymph node enlargement. While HD, reactive hyperplasia and tuberculosis were commonest in young adult patients (10-29 years old) and rare above the age of 50 years; NHL was the predominant cause of lymph node enlargement above 50 years. Conclusions: Lymph node biopsy plays an important role in establishing the cause of lymphadenopathy. Among the biopsied nodes, lymphomas were the most common (44.3%) followed by non-specific reactive hyperplasia (23.5%) and tuberculous lymphadenitis (14.2%).

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Section: Discussionmentioning

confidence: 66%

Pattern of Lymph Node Pathology in Western Saudi Arabia

Albasri

El-Siddig²,

Hussainy³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…Meanwhile, in a study done South India, there was a significant female majority of 2.4:1 9 . However, a gender comparison of 1:1 was observed in the results obtained from a study conducted in Italy, in September 2016 5 .…”

Section: Resultsmentioning

confidence: 99%

“…Even though, this disease almost always runs a benign course and resolves in several weeks to months in most patients 6,9 , it is seen to increase the risk of SLE and lymphoma 7 . Treatment if necessary is symptomatic with analgesics and antipyretics 1 .…”

Section: Introductionmentioning

confidence: 99%

Kikuchi-Fujimoto Disease: A Study Of 67 Cases From Coastal South India 

Achappa¹,

Herath²,

Kini³

et al. 2020

Preprint

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Background Kikuchi-Fujimoto disease is a rare, benign condition, of unknown etiology, presenting as cervical lymphadenitis, usually tender and maybe associated with systemic symptoms. Despite the extensive literature on this disease, it continues to be misdiagnosed owing to its misleading clinical presentation. Results The mean age in our study was 26.9 (±11.3) years with a female majority of 65.7%. The clinical presentation of most cases was, tender swelling over the side of the neck ( n =50, 74.6%). On local examination, the mean length and width were 2.3 (±1.0) cm and 2.2 (±0.7) cm respectively. Histopathological examination revealed that most patients presented in the proliferative stage ( n =40, 59.7%). In 83.6% of the patients lymphadenopathy resolved in less than 2 months. Follow up of these patients over 9 months revealed that a vast majority of the patients underwent full recovery with symptomatic treatment ( n =42, 62.7%). Conclusions The disease is prevalent in young, female patients of Asian descent and often presents as cervical lymphadenopathy. Early diagnosis with excisional lymph node biopsy is crucial to avoid unnecessary investigations and treatment. Treatment is only symptomatic unless complicated, where steroid therapy is considered. Kikuchi’s disease has an excellent prognosis with almost no risk of fatality.

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“…Involvement of other LN sites is less common [10]. Painless cervical lymphadenopathy was the most common presenting features in an Indian case series reported by Supari D et al Other constitutional features include fatigue, anorexia, sore throat, arthralgia, night sweats and skin rash [11]. There are certain cases of KFD that have presented as fever of unknown origin (FUO) [4].…”

Section: Discussionmentioning

confidence: 99%

Kikuchi- Fujimoto Disease: A Rare Cause of Lymphadenopathy

Anuradha¹,

Vanlalmalsawmdawngliana²,

Khurana³

2017

JCR

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Background: Kikuchi-Fujimoto disease (KFD) also known as histiocytic necrotizing lymphadenitis is a rare and self-limiting cause of fever with lymphadenitis. It usually affects females of the reproductive age group with a predominant involvement of cervical lymph nodes. Case Report: We report a case of young boy with Kikuchi-Fujimoto disease who presented with prolonged fever and painless cervical lymphadenopathy. Conclusion: Due to numerous causes of lymphadenopathy, patients are likely to be misdiagnosed with another disease. A high clinical suspicion with histopathological confirmation is essential for early and accurate diagnosis of KFD, which is usually a self-limited condition.

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Kikuchi–Fujimoto Disease: A Study of 24 Cases

Cited by 11 publications

References 13 publications

Pattern of Lymph Node Pathology in Western Saudi Arabia

Pattern of Lymph Node Pathology in Western Saudi Arabia

Kikuchi-Fujimoto Disease: A Study Of 67 Cases From Coastal South India

Kikuchi- Fujimoto Disease: A Rare Cause of Lymphadenopathy

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Kikuchi–Fujimoto Disease: A Study of 24 Cases

Cited by 11 publications

References 13 publications

Pattern of Lymph Node Pathology in Western Saudi Arabia

Pattern of Lymph Node Pathology in Western Saudi Arabia

Kikuchi-Fujimoto Disease: A Study Of 67 Cases From Coastal South India&nbsp;

Kikuchi- Fujimoto Disease: A Rare Cause of Lymphadenopathy

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Kikuchi-Fujimoto Disease: A Study Of 67 Cases From Coastal South India