Kikuchi Fujimoto disease: sinister presentation, good prognosis

Abstract

Kikuchi-Fujimoto disease (KFD) is a rare, benign, self-limiting necrotizing lymphadenitis of unknown etiology. The disease can affect people of all ages and of any sex and ethnicity. Tissue biopsy is needed for accurate diagnosis. The condition commonly masquerades as more sinister conditions such as malignancy and rheumatologic disorders, but has a much better prognosis. Treatment is generally supportive but patients may require corticosteroids with eventual spontaneous resolution. We discuss a case of KFD in a 34-year-old male and highlight the need for prompt and accurate diagnosis.

La enfermedad de Kikuchi-Fujimoto: una gran imitadora. A propósito de un caso

“…La patogénesis exacta no está completamente comprendida, ésta se relaciona con infecciones virales o con un sustrato autoinmune desencadenante de la enfermedad. La teoría autoinmune sugiere una respuesta inmunomediada de las células T a antígenos específicos, en personas genéticamente susceptibles 10 .…”