Kimura's disease: A case report and literature review

Gumbs, Milton A.; Pai, Narayan; Saraiya, R J; Rubinstein, Joshua; Vythilingam, Lakshmy; Choi, Young Hwan

doi:10.1002/(sici)1096-9098(199903)70:3<190::aid-jso9>3.0.co;2-a

Cited by 28 publications

(13 citation statements)

References 12 publications

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“…Peripheral eosinophilia and the presence of eosinophils in the inflammatory infiltrate suggest that KD may be a hypersensitivity reaction. Some evidence has indicated that TH2 lymphocytes may also play a role, but further investigation is needed [12]. Treatment options range from conservative observation for asymptomatic patients to surgical excision, steroid therapy, and radiotherapy for symptomatic patients.…”

Section: Discussionmentioning

confidence: 99%

Kimura’s disease – a rare entity

Talwar¹,

Puri²

2013

Our Dermatol Online

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Introduction: Kimura's disease is a benign, but locally injurious disease with a marked predilection for the head and neck. Case Report: We present two cases of this rare disease. Discussion: Of uncertain aetiology, its tendency to present as a discrete, enlarging mass with associated lymphadenopathy makes it a condition of interest to clinicians who see head and neck pathology. Although rare, there are increasing numbers of reports of the condition and it should become part of the standard differential diagnosis.

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Section: Discussionmentioning

confidence: 99%

Kimura’s disease – a rare entity

Talwar¹,

Puri²

2013

Our Dermatol Online

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“…KD typically presents as a tumor-like mass in the head and neck region [1][2][3]. It is considered as a relatively rare lesion--both in whites and blacks--in the West, while it is endemic in Far East Asians [1,2,4,9]. It is more common in males [1,2,4,7,9].…”

Section: Discussionmentioning

confidence: 99%

“…It is considered as a relatively rare lesion--both in whites and blacks--in the West, while it is endemic in Far East Asians [1,2,4,9]. It is more common in males [1,2,4,7,9]. Even though, KD is mostly a head and neck lesion, few cases were reported in other locations e.g.…”

Section: Discussionmentioning

confidence: 99%

“…Even though, KD is mostly a head and neck lesion, few cases were reported in other locations e.g. axilla, trunk and groin [1,9,10]. Involvement of the epiglottis is very unusual and probably a very rare occurrence.…”

Section: Discussionmentioning

confidence: 99%

“…A very important histological differential diagnosis and pitfall to be avoided is ALHE. The important and helpful features differentiating KD from ALHE are summarized in (Table 2) [5,[7][8][9][10][11][12]. CD has characteristic ''onion-skin'' layering of the mantle zone with hyalinized blood vessels in the germinal centers.…”

Section: Discussionmentioning

confidence: 99%

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Kimura Disease of the Epiglottis

AbdullGaffar

Abdul-Haleem

Carlsen

2008

Head and Neck Pathol

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Kimura disease is a distinct clinicopathological entity of a benign chronic inflammatory disorder of unknown etiology. It is endemic in Oriental Asians, but sporadic and relatively rare in the West, both in whites and blacks alike. It usually presents as a mass lesion, most commonly in the head and neck region. It had for a long time been confused as synonymous with angiolymphoid hyperplasia with esinophilia. It can impose a challenging diagnosis both clinically and pathologically, especially in non-endemic areas with unusual sites involvement. Even though it is a benign lesion, it can be life-threatening in the epiglottis with a risk of airways obstruction. So far, one case had been reported in the epiglottis with upper respiratory tract obstruction. We report a similar case with a brief review of the literature.

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