Kinetic studies of tyrosinase inhibitory activity of 19 essential oils extracted from endemic and exotic medicinal plants

Aumeeruddy-Elalfi, Zaahira; Gurib-Fakim, Ameenah; Mahomoodally, Mohamad Fawzi

doi:10.1016/j.sajb.2015.09.010

Cited by 72 publications

(58 citation statements)

References 38 publications

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“…Against tyrosinase, Yemeni rosemary oil showed only 3.3% ± 1.5% inhibition at 100 μg/mL. In contrast, rosemary oil from cultivated plants from Mauritius did show tyrosinase inhibitory activity (median inhibitory concentration, IC 50 = 97 μg/mL) [101]. Rosemary oil was found to be relatively non-toxic to SK-OV-3, HO-8910, Bel-7402 (IC 50 ≥250 μg/mL) [102], MCF-7, LNCaP, and NIH-3T3 cells (IC 50 >180 μg/mL) [32], but active against A549 cells (IC 50 = 80 μg/mL) [103].…”

Section: Resultsmentioning

confidence: 99%

Chemotypic Characterization and Biological Activity of Rosmarinus officinalis

Satyal

Jones

Lopez

et al. 2017

Foods

112

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Rosemary (Rosmarinus officinalis L.) is a popular herb in cooking, traditional healing, and aromatherapy. The essential oils of R. officinalis were obtained from plants growing in Victoria (Australia), Alabama (USA), Western Cape (South Africa), Kenya, Nepal, and Yemen. Chemical compositions of the rosemary oils were analyzed by gas chromatography-mass spectrometry as well as chiral gas chromatography. The oils were dominated by (+)-α-pinene (13.5%–37.7%), 1,8-cineole (16.1%–29.3%), (+)-verbenone (0.8%–16.9%), (−)-borneol (2.1%–6.9%), (−)-camphor (0.7%–7.0%), and racemic limonene (1.6%–4.4%). Hierarchical cluster analysis, based on the compositions of these essential oils in addition to 72 compositions reported in the literature, revealed at least five different chemotypes of rosemary oil. Antifungal, cytotoxicity, xanthine oxidase inhibitory, and tyrosinase inhibitory activity screenings were carried out, but showed only marginal activities.

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Section: Resultsmentioning

confidence: 99%

Chemotypic Characterization and Biological Activity of Rosmarinus officinalis

Satyal

Jones

Lopez

et al. 2017

Foods

112

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“…EOs ability to inhibit this enzyme has been reported as competitive, non-competitive or mixed, based on their chemical composition [96]. Due to the complexity of the EO compositions, this activity is most probably attributable to a synergistic interaction of their compounds with the enzyme, rather than to a single component [97,98]. Contrary to published reports [96,99], however, the anti-tyrosinase activity does not seem correlated to the oxygenated monoterpenes fraction in the EOs composition: the two best performing ones in our assay were, indeed, the EOs with the lowest relative abundances of this chemical class of compounds.…”

Section: Discussionmentioning

confidence: 99%

Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants

et al. 2020

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In this study, the essential oils (EOs) of six Algerian plants (Artemisia campestris L., Artemisia herba-alba Asso, Juniperus phoenicea L., Juniperus oxycedrus L., Mentha pulegium L. and Lavandula officinalis Chaix) were obtained by hydrodistillation, and their compositions determined by GC-MS and GC-FID. The antioxidant activity of the EOS was evaluated via 2,2′-diphenyl-1-picrylhydrazyl (DPPH), ferric-reducing/antioxidant power (FRAP) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Moreover, their cytotoxic effect was evaluated—as well as their tyrosinase, acetyl- and butyryl-cholinesterase (AChE and BuChE) inhibitory activities. The chemical analyses detected 44, 45, 51, 53, 26 and 40 compounds in EOs of A. campestris, A. herba-alba, J. phoenicea, J. oxycedrus, M. pulegium and L. officinalis, respectively. A. campestris EO was mainly composed of β-pinene (20.7%), while A. herba-alba EO contained davanone D (49.5%) as the main component. α-Pinene (41.8%) was detected as the major constituent in both J. phoenicea (41.8%) and J. oxycedrus (37.8%) EOs. M. pulegium EO was characterized by pulegone as the most abundant (76.9%) compound, while linalool (35.8%) was detected as a major constituent in L. officinalis EO. The antioxidant power evaluation revealed IC50 values ranging from 2.61 to 91.25 mg/mL for DPPH scavenging activity, while the FRAP values ranged from 0.97–8.17 µmol Trolox equivalents (TX)/g sample. In the ABTS assay, the values ranged from 7.01 to 2.40 µmol TX/g sample. In the presence of 1 mg/mL of the samples, tyrosinase inhibition rates ranged from 11.35% to 39.65%, AChE inhibition rates ranged from 40.57% to 73.60% and BuChE inhibition rates ranged from 6.47% to 72.03%. A significant cytotoxic effect was found for A. herba-alba EO. The obtained results support some of the traditional uses of these species in food preservation and for protection against several diseases.

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“…The pomelo ( Citrus grandis (L.) Osbeck), belonging to the Rutaceae family, is a tropical and subtropical fruit. In some places, pomelo is not only a fruit but is also used in folk medicine against fatigue, loss of energy, lack of vitality, bruising, wounds, acne, or mild skin disorders [ 1 ]. Several varieties of pomelo are present in Taiwan.…”

Section: Introductionmentioning

confidence: 99%

Composition and Bioactivity of Essential Oil from Citrus grandis (L.) Osbeck ‘Mato Peiyu’ Leaf

et al. 2017

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‘Mato Peiyu’ pomelo (Citrus grandis (L.) Osbeck ‘Mato Peiyu’) leaves from pruning are currently an agricultural waste. The aim of this study was to isolate essential oils from these leaves through steam distillation (SD) and solvent-free microwave extraction (SFME) and to evaluate their applicability to skin care by analyzing their antimicrobial, antioxidant (diphenyl-1-picrylhydrazyl scavenging assay, β-carotene/linoleic acid assay, and nitric oxide scavenging assay), anti-inflammatory (5-lipoxygenase inhibition assay), and antityrosinase activities. The gas chromatography–mass spectrometry results indicated that the main components of ‘Mato Peiyu’ leaf essential oils were citronellal and citronellol, with a total percentage of 50.71% and 59.82% for SD and SFME, respectively. The highest bioactivity among all assays was obtained for 5-lipoxygenase inhibition, with an IC50 value of 0.034% (v/v). The MIC90 of the antimicrobial activity of essential oils against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans ranged from 0.086% to 0.121% (v/v). Citronellal and citronellol were the main contributors, accounting for at least 54.58% of the essential oil’s bioactivity. This paper is the first to report the compositions and bioactivities of ‘Mato Peiyu’ leaf essential oil, and the results imply that the pomelo leaf essential oil may be applied in skin care.

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Kinetic studies of tyrosinase inhibitory activity of 19 essential oils extracted from endemic and exotic medicinal plants

Cited by 72 publications

References 38 publications

Chemotypic Characterization and Biological Activity of Rosmarinus officinalis

Chemotypic Characterization and Biological Activity of Rosmarinus officinalis

Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants

Composition and Bioactivity of Essential Oil from Citrus grandis (L.) Osbeck ‘Mato Peiyu’ Leaf

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