Kinetic Study of Modification of Collegen Peptide with Allyl Glycidyl Ether

Abstract

The kinetics of reaction of collagen peptide with allyl glycidyl ether (AGE), and their temperature dependence, were studied by monitoring the reduction of the primary amine groups as a function of time. A kinetic model, with a second order with respect to the primary amine groups of collagen peptide and a first-order dependence on AGE, was developed that gave a good fit to the experimental data.