Kinetics of formation of anhydrovitamin A from vitamin A alcohol and its acetate**School of Pharmacy, University of Wisconsin, Madison

The stability during normal use of vitamin A, vitamin C and thiamine in 6 liquid multivitamin preparations has been examined. Three samples were below label claim when purchased but no further losses occurred during storage of unopened bottles. Destruction of the vitamins was increased by daily removal of a portion of the contents and the stability of most samples stored at room temperature was unsatisfactory. The study suggests that the results of stability tests should be examined more critically to ensure not only that the products meet label claim when purchased, but also maintain a satisfactory potency during normal use. From the consumer's point of view the use of expiration dates which take account of loss during normal use would be most valuable. The finding of retrovitamin A in one preparation suggests the need for more detailed study of the complex changes which may take place in these preparations during storage and of methods to evaluate such changes.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Kinetics of formation of anhydrovitamin A from vitamin A alcohol and its acetate**School of Pharmacy, University of Wisconsin, Madison

Cited by 6 publications

References 5 publications

Degradation Mechanisms for Water-Soluble Drugs in Solid Dosage Forms

Degradation Mechanisms for Water-Soluble Drugs in Solid Dosage Forms

Degradation of retinyl acetate in simple solvent systems

The Stability of Liquid Multivitamin Preparations During Use

Contact Info

Product

Resources

About